Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 3/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329871 | 0.87 | RPS6KA2 (0.48) | CYP1A2CYP2C9CYP2C19ALDH1A1CASP3 | |
| SCHEMBL17983321 | 0.83 | ACHE (0.48) | CYP1A2CYP2C19CA12CA9ALDH1A1 | |
| SCHEMBL17983134 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19ALDH1A1RAB9A | |
| SCHEMBL17983041 | 0.81 | MGLL (0.44) | ALDH1A1MAPT | |
| SCHEMBL17983139 | 0.80 | RGS4 (0.34) | CYP1A2CYP2C9CYP2C19ALDH1A1ACHE | |
| SCHEMBL17983325 | 0.79 | RAB9A (0.41) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11253482 | 0.79 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19CA12CA9 | |
| SCHEMBL9551116 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19CA12CA9 | |
| SCHEMBL3785657 | 0.76 | CA12 (0.43) | CYP1A2CYP2C9CYP2C19CA12CA9 | |
| SCHEMBL17983076 | 0.76 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540463-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2017-01-10 | — | — | US | claimed |
| US-20160237186-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2016-08-18 | — | — | US | claimed |
| US-9540463-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2017-01-10 | — | — | US | disclosed |
| US-20160237186-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2016-08-18 | — | — | US | disclosed |
| EP-1683791-B1 | Process for the epoxidation of olefins with hydrogen peroxide by ruthenium complex catalysed reaction | SALTIGO GMBH (DE) | 2008-04-02 | — | — | EP | disclosed |
| CN-1817871-A | Process for the ruthenium-catalyzed epoxidation of olefins with the aid of hydrogen peroxide | LANXESS DEUTSCHLAND GMBH (DE) | 2006-08-16 | — | — | CN | disclosed |
| EP-1683791-A1 | Process for the epoxidation of olefins with hydrogen peroxide by ruthenium complex catalysed reaction | Lanxess Deutschland GmbH (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20060161011-A1 | Process for the ruthenium-catalysed epoxidation of olefins by means of hydrogen peroxide | LANXESS DEUTSCHLAND GMBH (DE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060161011-A1 | Process for the ruthenium-catalysed epoxidation of olefins by means of hydrogen peroxide | PPOX, HAO2, GPX4 | CYP1A2 151/4885CYP2C9 391/4885CYP2C19 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.