Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 14/20 | 0.54 |
| ▸ | THRB | P10828 | 14/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14311297 | 0.83 | ALOX5 (0.56) | THRATHRBTSHRHSD17B10 | |
| SCHEMBL3687250 | 0.82 | THRA (0.43) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL18886561 | 0.82 | ALDH1A1 (0.48) | THRATHRBCYP2C9TSHRHIF1A | |
| SCHEMBL11372198 | 0.82 | THRA (0.53) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL6293628 | 0.79 | THRA (0.55) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL7873997 | 0.79 | CYP3A4 (0.55) | CYP2C9TSHRHIF1AHSD17B10PTPN1 | |
| SCHEMBL5670212 | 0.79 | KEAP1 (0.64) | THRATHRBKEAP1FFAR1 | |
| SCHEMBL3689346 | 0.79 | CA1 (0.51) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL17672986 | 0.78 | KEAP1 (0.52) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL5858355 | 0.78 | THRB (0.56) | THRATHRBCYP2C9TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242622-B1 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECH RES LTD (GB) | 2008-06-18 | — | — | EP | disclosed |
| US-7169554-B2 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | GEN-PROBE INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| EP-0709466-B1 | Compositions and methods for the simultaneous detection and quantification of multiple specific nucleic acid sequences | GEN PROBE INC (US) | 2006-09-27 | — | — | EP | disclosed |
| US-20030082713-A1 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | THIRD WAVE TECHNOLOGIES, INC. | 2003-05-01 | — | — | US | disclosed |
| EP-1242622-A2 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | Molecular Light Technology Research Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042497-A9 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECH RES LTD (GB) | 2002-06-06 | — | — | WO | disclosed |
| WO-2001042497-A2 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECHNOLOGY RESEARCH LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |
| US-5840873-A | PLURALITY OF DIFFERENT OLIGONUCLEOTIDE PROBES EACH COUPLED TO DIFFERENT CHEMILUMINESCENT LABEL | GEN-PROBE INCORPORATED (US) | 1998-11-24 | — | — | US | disclosed |
| US-5827656-A | UTILIZING OLIGONUCLEOTIDE HYBRIDIZATION PROBE COUPLED TO DIFFERENT CHEMILUMINESCENT ACRIDINIUM ESTER LABELS WHICH HYBRIDIZES TO NUCLEIC ACID ANALYTES | GEN-PROBE INCORPORATED (US) | 1998-10-27 | — | — | US | disclosed |
| US-5756709-A | PLURALITY OF DIFFERENT OLIGONUCLEOTIDE HYBRIDIZATION PROBES EACH COUPLED TO DIFFERENT CHEMILUMINESCENT LABELS | GEN-PROBE INCORPORATED (US) | 1998-05-26 | — | — | US | disclosed |
| US-5658737-A | KIT CONTAINING OLIGONUCLEOTIDE HYBRIDIZATION ASSAY PROBES ABLE TO HYBRIDIZE TO DIFFERENT NUCLEIC ACID TARGET ANALYTES, EACH COUPLED WITH DIFFERENT CHEMILUMINESCENT LABEL | GEN-PROBE INCORPORATED (US) | 1997-08-19 | — | — | US | disclosed |
| WO-1996013612-A2 | COMPOSITIONS AND METHODS FOR THE SIMULTANEOUS DETECTION AND QUANTIFICATION OF MULTIPLE SPECIFIC NUCLEIC ACID SEQUENCES | GEN-PROBE INCORPORATED (US) | 1996-05-09 | — | — | WO | disclosed |
| EP-0709466-A2 | Compositions and methods for the simultaneous detection and quantification of multiple specific nucleic acid sequences | GEN-PROBE INCORPORATED (US) | 1996-05-01 | — | — | EP | disclosed |
| US-4031087-A | INSECTICIDES | SHELL OIL COMPANY (US) | 1977-06-21 | — | — | US | disclosed |