SCHEMBL4630715

SCHEMBL4630715

CCCCC(Cl)[SiH](OC)OC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ALDH1A1 P00352 2/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17668935 0.93 OPRM1 (0.36) DNM1
SCHEMBL17669045 0.91 ZDHHC7 (0.37) DNM1ALDH1A1
SCHEMBL2448728 0.85
SCHEMBL320980 0.85
SCHEMBL17669034 0.79 DNM1 (0.32) DNM1
SCHEMBL15015681 0.79 ENPEP (0.31)
SCHEMBL8470115 0.75 DNM1 (0.42) DNM1CA1CA2ALDH1A1TDP1
SCHEMBL319730 0.74
SCHEMBL2088586 0.73 DNM1 (0.35) DNM1CA1CA2ALDH1A1TDP1
SCHEMBL17669051 0.73 OPRM1 (0.39) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3009439-B1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD SHINETSU CHEMICAL CO (JP) 2018-01-03 EP disclosed
US-9371341-B2 Cyclic aminoorganoxysilane compound and its production method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-06-21 US disclosed
EP-3009439-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD Shin-Etsu Chemical Co., Ltd. (JP) 2016-04-20 EP disclosed
US-20160102111-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-04-14 US disclosed
EP-1922324-B1 PROCESS FOR PRODUCING ORGANOALKOXYSILANES FROM ORGANIC ACIDS OR CYANATES AND HALOALKYLALKOXYSILNANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-07-17 EP disclosed
EP-1922324-A1 PROCESS FOR PRODUCING ORGANOALKOXYSILANES FROM ORGANIC ACIDS OR CYANATES AND HALOALKYLALKOXYSILNANES Momentive Performance Materials Inc. (US) 2008-05-21 EP disclosed
US-7262312-B2 Process for producing organoalkoxysilanes from organic acids or cyanates and haloalkylalkoxysilanes MOMENTIVE PERFORMANCE MATERIALS INC. 2007-08-28 US disclosed
WO-2007018997-A1 PROCESS FOR PRODUCING ORGANOALKOXYSILANES FROM ORGANIC ACIDS OR CYANATES AND HALOALKYLALKOXYSILNANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-02-15 WO disclosed
US-20070032673-A1 PROCESS FOR PRODUCING ORGANOALKOXYSILANES FROM ORGANIC ACIDS OR CYANATES AND HALOALKYLALKOXYSILANES MOMENTIVE PERFORMANCE MATERIALS INC. 2007-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032673-A1 PROCESS FOR PRODUCING ORGANOALKOXYSILANES FROM ORGANIC ACIDS OR CYANATES AND HALOALKYLALKOXYSILANES OGA, ALKBH3, SLC43A1 DNM1 4225/4885CA1 344/4885CA2 19/4885
US-20160102111-A1 CYCLIC AMINOORGANOXYSILANE COMPOUND AND ITS PRODUCTION METHOD BCAT2, BCAT1, AKR1B10 DNM1 3942/4885CA1 948/4885CA2 2229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.