Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GUCY1B2 | O75343 | 2/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 2/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 2/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407391 | 1.00 | CTSK (0.34) | CTSKKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL439064 | 0.83 | DPP4 (0.33) | KDM4ELMNAHTTSMN1; SMN2ENPP2 | |
| SCHEMBL441391 | 0.81 | ENPP2 (0.31) | ENPP2DPP4MEN1KMT2A | |
| SCHEMBL408945 | 0.77 | LIPE (0.33) | CTSKKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL463714 | 0.77 | LIPE (0.33) | CTSKKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL408912 | 0.77 | LIPE (0.33) | CTSKKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL406761 | 0.74 | PKM (0.40) | DPP4MEN1KMT2A | |
| SCHEMBL16797579 | 0.72 | CYP2C19 (0.38) | KDM4ELMNAHTTSMN1; SMN2ENPP2 | |
| SCHEMBL12940206 | 0.69 | ALDH1A1 (0.34) | KDM4EENPP2ALDH1A1L3MBTL1GAA | |
| SCHEMBL407345 | 0.69 | PKM (0.37) | CTSKKDM4ESMN1; SMN2ENPP2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | CTSK 3044/4885KDM4E 2452/4885LMNA 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.