Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637260 | 0.81 | FFAR1 (0.39) | FFAR1KMT2A | |
| SCHEMBL4637327 | 0.81 | FFAR1 (0.43) | FFAR1KMT2AIDO1 | |
| SCHEMBL4637290 | 0.78 | ALDH1A1 (0.51) | FFAR1KMT2AIDO1DRD1GID4 | |
| SCHEMBL7425981 | 0.77 | KMT2A (0.47) | FFAR1KMT2AIDO1HTR2ADRD1 | |
| SCHEMBL15490529 | 0.74 | CA12 (0.48) | KMT2AHTR2A | |
| SCHEMBL3546305 | 0.70 | MTNR1A (0.55) | KMT2ADRD1GID4ATMTSHR | |
| SCHEMBL11998990 | 0.69 | FFAR1 (0.60) | FFAR1IDO1 | |
| SCHEMBL227440 | 0.68 | DRD2 (0.47) | HTR2A | |
| SCHEMBL7425987 | 0.67 | SMPD1 (0.47) | IDO1ATMKDM4E | |
| SCHEMBL21142124 | 0.66 | IDO1 (0.54) | FFAR1IDO1GID4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468991-B1 | Imides as PDE III, PDE IV and TNF inhibitors | CELGENE CORP (US) | 2008-02-20 | — | — | EP | disclosed |
| EP-1468991-A1 | Imides as PDE III, PDE IV and TNF inhibitors | CELGENE CORPORATION (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0874819-B1 | IMIDES AS PDE III, PDE IV AND TNF INHIBITORS | CELGENE CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| US-5728844-A | INHIBITORS OF TUMOR NECROSIS AND PHOSPHODIESTERASE | CELGENE CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |