Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MARS1 | P56192 | 2/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637971 | 0.87 | CYP19A1 (0.50) | CYP19A1ALDH1A1TSHRP2RX7IDH1 | |
| SCHEMBL4639451 | 0.86 | CYP19A1 (0.48) | CYP19A1ALDH1A1TSHRP2RX7HPGD | |
| SCHEMBL4637702 | 0.84 | PTGER4 (0.44) | CYP19A1ALDH1A1TSHRP2RX7HPGD | |
| SCHEMBL4639434 | 0.84 | CYP19A1 (0.42) | CYP19A1ALDH1A1TSHRP2RX7L3MBTL1 | |
| SCHEMBL4637742 | 0.84 | ALDH1A1 (0.52) | CYP19A1ALDH1A1TSHRP2RX7HPGD | |
| SCHEMBL4638551 | 0.83 | IDH1 (0.55) | CYP19A1ALDH1A1TSHRP2RX7HPGD | |
| SCHEMBL4638811 | 0.81 | IDH1 (0.40) | CYP19A1ALDH1A1TSHRP2RX7L3MBTL1 | |
| SCHEMBL4638668 | 0.80 | POLB (0.51) | CYP19A1ALDH1A1P2RX7L3MBTL1IDH1 | |
| SCHEMBL4707264 | 0.75 | RORB (0.49) | ALDH1A1P2RX7L3MBTL1IDH1CYP2E1 | |
| SCHEMBL4638808 | 0.75 | P2RX7 (0.38) | ALDH1A1P2RX7L3MBTL1IDH1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |