Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.40 |
| ▸ | HTR1F | P30939 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641252 | 0.90 | PTGDR2 (0.39) | PTGDR2HTR1FMCHR1MAPTHTR1A | |
| SCHEMBL5246991 | 0.88 | HTR1F (0.42) | PTGDR2HTR1FMCHR1POLBMAPT | |
| SCHEMBL4641260 | 0.87 | MCHR1 (0.38) | PTGDR2MCHR1CHRM3 | |
| SCHEMBL4641368 | 0.87 | PTGDR2 (0.40) | PTGDR2HTR1FMCHR1POLBMAPT | |
| SCHEMBL4643611 | 0.86 | SMN1; SMN2 (0.39) | PTGDR2MCHR1POLBMAPT | |
| SCHEMBL4642981 | 0.85 | NPC1 (0.38) | PTGDR2MCHR1POLBMAPT | |
| SCHEMBL4644568 | 0.84 | CASP3 (0.39) | PTGDR2MCHR1MAPT | |
| SCHEMBL4641302 | 0.84 | MAPT (0.42) | PTGDR2MCHR1POLBMAPT | |
| SCHEMBL4646542 | 0.82 | MCHR1 (0.41) | PTGDR2MCHR1MAPTCHRM3 | |
| SCHEMBL4641270 | 0.82 | MAPT (0.40) | MCHR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |