Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646174 | 0.82 | KMT2A (0.39) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL4648361 | 0.78 | ITGB2 (0.40) | CYP2C19NPC1NPSR1KMT2AMAPT | |
| SCHEMBL4645997 | 0.72 | MAPT (0.50) | CYP1A2CYP2C19CYP2C9MAPK1HTT | |
| SCHEMBL4647900 | 0.71 | EPHX1 (0.35) | CYP1A2CYP3A4CYP2C19EPHX1IDO1 | |
| SCHEMBL4646831 | 0.71 | LMNA (0.40) | CYP1A2CYP3A4CYP2C19CYP2C9HTT | |
| SCHEMBL4647489 | 0.71 | CYP2D6 (0.39) | CYP1A2CYP3A4CYP2C19IDO1SMN1; SMN2 | |
| SCHEMBL4646887 | 0.71 | EPHX1 (0.44) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL4645168 | 0.70 | ALDH1A1 (0.39) | HTTHPGDNPSR1KMT2AMAPT | |
| SCHEMBL4645967 | 0.69 | SMN1; SMN2 (0.34) | SMN1; SMN2NPC1HPGDKMT2AMAPT | |
| SCHEMBL4647260 | 0.69 | BCHE (0.39) | IDO1HTTNPC1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |