SCHEMBL464633

SCHEMBL464633

O=C(/C=C(\O)c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 1.00
MAPT P10636 3/20 0.64
KDM4E B2RXH2 1/20 0.64
CYP3A4 P08684 1/20 0.64
HPGD P15428 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
CA12 O43570 1/20 0.64
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
CA9 Q16790 1/20 0.64
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
ALDH1A1 P00352 3/20 0.58
MAPK1 P28482 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
HDAC1 Q13547 2/20 0.57
HDAC2 Q92769 2/20 0.57
HDAC3 O15379 1/20 0.57
NCOR2 Q9Y618 1/20 0.57
AKT1 P31749 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3244802 1.00 NFE2L2 (1.00) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL6426228 1.00 NFE2L2 (1.00) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL30356358 0.98 NFE2L2 (0.95) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL29994107 0.98 NFE2L2 (0.95) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL15455955 0.98 NFE2L2 (0.95) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL15455953 0.98 NFE2L2 (0.95) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL31236160 0.98 NFE2L2 (0.95) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL7865886 0.89 NFE2L2 (0.80) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL17268310 0.88 NFE2L2 (0.77) NFE2L2MAPTKDM4ECYP3A4HPGD
SCHEMBL28387778 0.88 NFE2L2 (0.77) NFE2L2MAPTKDM4ECYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210230090-A1 METAL COMPLEXES OF B-DIKETONES AND/OR POLYPHENOLS BY GREEN CHEMISTRY, PREPARATION METHOD THEREOF, SUNSCREEN THEREOF, SKIN OR HAIR TONE CONCEALER THEREOF, HAIR DYEING THEREOF AND OTHER USES THEREOF RAMIREZ RIOS LILIANA PATRICIA (NL) 2021-07-29 US claimed
EP-3807287-A1 METAL COMPLEXES OF BETA-DIKETONES AND/OR POLYPHENOLS BY GREEN CHEMISTRY, PREPARATION METHOD THEREOF, SUNSCREEN THEREOF, SKIN OR HAIR TONE CONCEALER THEREOF, HAIR DYEING THEREOF AND OTHER USES THEREOF RAMIREZ RIOS, Liliana Patricia (NL) 2021-04-21 EP claimed
WO-2019238261-A1 METAL COMPLEXES OF β-DIKETONES AND/OR POLYPHENOLS BY GREEN CHEMISTRY, PREPARATION METHOD THEREOF, SUNSCREEN THEREOF, SKIN OR HAIR TONE CONCEALER THEREOF, HAIR DYEING THEREOF AND OTHER USES THEREOF RAMIREZ RIOS LILIANA PATRICIA (NL) 2019-12-19 WO claimed
WO-2024142881-A1 METAL COMPLEX AND ORGANIC ELECTROLUMINESCENT ELEMENT キヤノン株式会社 2024-07-04 WO disclosed
US-20230329081-A1 Light Emitting Device and Composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-12 US disclosed
WO-2023181738-A1 COMPOSITION AND METHOD FOR MANUFACTURING LIGHT-EMITTING ELEMENT USING SAME 住友化学株式会社 2023-09-28 WO disclosed
US-11770941-B2 Film production method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-26 US disclosed
US-11770941-B2 Film production method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-26 US disclosed
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PROMERUS, LLC (US) 2023-09-19 US disclosed
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PROMERUS, LLC (US) 2023-09-19 US disclosed
EP-3680945-B1 LIGHT EMITTING ELEMENT SUMITOMO CHEMICAL CO (JP) 2023-09-06 EP disclosed
US-20070060644-A1 Therapeutic curcumin derivatives STC.UNM 2007-03-15 US disclosed
US-20070060644-A1 Therapeutic curcumin derivatives STC.UNM 2007-03-15 US disclosed
US-20070037083-A1 Positive electrified charge control agent and charge control method of toner using it ORIENT CHEMICAL INSUSTRIES, LTD. (JP) 2007-02-15 US disclosed
US-20060073357-A1 Carbazole compounds and use of such compounds in organic electroluminiscent devices KONINKLIJKE PHILIPS ELECTRONICS, N.V. (NL) 2006-04-06 US disclosed
US-20060051611-A1 Electroluminescent device KONINKLIJKE PHILIPS ELECTRONICS N.V. 2006-03-09 US disclosed
EP-1594939-A2 CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES Koninklijke Philips Electronics N.V. (NL) 2005-11-16 EP disclosed
EP-1572832-A1 ELECTROLUMINESCENT DEVICE Koninklijke Philips Electronics N.V. (NL) 2005-09-14 EP disclosed
WO-2004072205-A2 CARBAZOLE COMPOUNDS AND USE OF SUCH COMPOUNDS IN ORGANIC ELECTROLUMINESCENT DEVICES KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-08-26 WO disclosed
WO-2004055129-A1 ELECTROLUMINESCENT DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2004-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070060644-A1 Therapeutic curcumin derivatives FABP2, GLS2, FABP1 NFE2L2 75/4885MAPT 448/4885KDM4E 3658/4885
US-20210230090-A1 METAL COMPLEXES OF B-DIKETONES AND/OR POLYPHENOLS BY GREEN CHEMISTRY, PREPARATION METHOD THEREOF, SUNSCREEN THEREOF, SKIN OR HAIR TONE CONCEALER THEREOF, HAIR DYEING THEREOF AND OTHER USES THEREOF TYR, FABP4, TDO2 NFE2L2 162/4885MAPT 506/4885KDM4E 87/4885
US-11760817-B2 Mass polymerizable polycycloolefin compositions containing soluble photoacid generators PPOX, VCL, PFN1 NFE2L2 2306/4885MAPT 906/4885KDM4E 3000/4885
US-20070037083-A1 Positive electrified charge control agent and charge control method of toner using it H1-4, CHD1, SPTAN1 NFE2L2 3131/4885MAPT 1712/4885KDM4E 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.