Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641410 | 0.95 | AGPAT2 (0.42) | AGPAT2MAPTROCK2THRBKDR | |
| SCHEMBL4643048 | 0.93 | AGPAT2 (0.42) | AGPAT2MAPTTHRBPOLB | |
| SCHEMBL4643098 | 0.92 | MAPT (0.46) | AGPAT2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL13054298 | 0.88 | MAPT (0.49) | MAPTTHRBKDRPOLBSLC2A1 | |
| Hydrochloric Acid SCHEMBL5249326 | 0.88 | MAPT (0.49) | MAPTTHRBKDRPOLBSLC2A1 | |
| SCHEMBL4641300 | 0.87 | AGPAT2 (0.42) | AGPAT2MAPTTHRBKDRKDM4E | |
| SCHEMBL4641368 | 0.87 | PTGDR2 (0.40) | MAPTTHRBPTGDR2POLB | |
| SCHEMBL4643045 | 0.87 | CHRM3 (0.40) | AGPAT2MAPTTHRBKDRKDM4E | |
| SCHEMBL4646624 | 0.86 | MAPT (0.42) | MAPTTHRBKDM4EALDH1A1HPGD | |
| SCHEMBL4644568 | 0.83 | CASP3 (0.39) | AGPAT2MAPTTHRBKDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | claimed |