Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTR5A | P47898 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24421700 | 0.83 | ALDH1A1 (0.56) | MAPTALDH1A1GAAHSD17B10USP2 | |
| SCHEMBL4649484 | 0.81 | HTR3A (0.69) | HTR3AMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL2224540 | 0.80 | DRD2 (0.58) | MAPTALDH1A1GAAHTR7LMNA | |
| SCHEMBL30480093 | 0.78 | TERT (0.55) | HTR3AMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL7723267 | 0.78 | TERT (0.55) | HTR3AMAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL15534608 | 0.76 | MAPT (0.56) | MAPTALDH1A1GAALMNAHTT | |
| SCHEMBL24421699 | 0.75 | ESR1 (0.43) | HTR3AMAPTALDH1A1GAALMNA | |
| SCHEMBL1905445 | 0.75 | MAPT (0.48) | HTR3AMAPTALDH1A1GAALMNA | |
| SCHEMBL4649483 | 0.75 | MAPT (0.59) | MAPTALDH1A1GAAHSD17B10LMNA | |
| SCHEMBL13153256 | 0.73 | ADRB1 (0.58) | HTR3AMAPTALDH1A1GAAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177253-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-11-28 | — | — | WO | disclosed |