SCHEMBL29205

SCHEMBL29205

COc1ccc(C(O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.54
AHR P35869 2/20 0.54
LTA4H P09960 2/20 0.52
KIF11 P52732 5/20 0.51
KCNH2 Q12809 1/20 0.51
ACSS2 Q9NR19 2/20 0.49
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KMT2A Q03164 1/20 0.47
TRPA1 O75762 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28797 1.00 CA4 (0.54) CA4AHRLTA4HKIF11KCNH2
SCHEMBL12199475 0.92 KIF11 (0.56) CA4AHRLTA4HKIF11KCNH2
SCHEMBL3855634 0.92 ESR2 (0.53) CA4AHRLTA4HKIF11KCNH2
SCHEMBL812742 0.91 CA1 (0.58) AHRLTA4HCES2CES1CA12
SCHEMBL8986531 0.89 AHR (0.57) AHRKIF11KCNH2ACSS2LMNA
SCHEMBL18383079 0.88 LTA4H (0.55) CA4AHRLTA4HKIF11KCNH2
SCHEMBL8824303 0.88 CA1 (0.67) CES2CES1CA1CA2LMNA
SCHEMBL18027607 0.88 LTA4H (0.50) AHRLTA4HKIF11KCNH2ACSS2
SCHEMBL18387604 0.88 ACSS2 (0.50) AHRLTA4HKIF11KCNH2ACSS2
SCHEMBL7763666 0.87 CA4 (0.54) CA4LTA4HKIF11KCNH2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND AARHUS UNIVERSITET (DK) 2023-10-05 US claimed
EP-4182325-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND Aarhus Universitet (DK) 2023-05-24 EP claimed
US-20220304980-A1 METERED DOSING COMPOSITIONS AND METHODS OF USE OF PSYCHEDELIC COMPOUNDS MARLEY GREEN, LLC 2022-09-29 US claimed
WO-2022013393-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND AARHUS UNIVERSITET (DK) 2022-01-20 WO claimed
CN-112430179-A High-efficiency separation and purification method of 4,4 '-dimethoxytriphenylchloromethane and 4,4' -dimethoxytrityl alcohol 连云港冠昕医药科技有限公司 2021-03-02 CN claimed
EP-1975256-B1 Modified oligonucleotides for mismatch discrimination EPOCH BIOSCIENCES INC (US) 2012-07-11 EP claimed
EP-1261616-B1 MODIFIED OLIGONUCLEOTIDES FOR MISMATCH DISCRIMINATION EPOCH BIOSCIENCES INC (US) 2010-08-18 EP claimed
EP-1975256-A1 Modified oligonucleotides for mismatch discrimination Epoch Biosciences, Inc. (US) 2008-10-01 EP claimed
US-7045610-B2 Modified oligonucleotides for mismatch discrimination EPOCH BIOSCIENCES, INC. (US) 2006-05-16 US claimed
US-20060009628-A1 MODIFIED OLIGONUCLEOTIDES FOR MISMATCH DISCRIMINATION ELITECHGROUP, INC. 2006-01-12 US claimed
US-5204218-A Triphenylmethanol photobase generators and base-catalytic reaction compound MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1993-04-20 US claimed
CN-122094698-A Ligands for extrahepatic delivery of siRNA 2026-05-26 CN disclosed
US-12590330-B2 Methods for indexing samples and sequencing multiple polynucleotide templates ILLUMINA CAMBRIDGE LIMITED (GB) 2026-03-31 US disclosed
US-20260083759-A1 Combinations Comprising Psychedelics for the Treatment of Schizophrenia and Other Neuropsychiatric and Neurologic Disorders HADASIT MED RES SERVICE (IL) 2026-03-26 US disclosed
US-12378276-B2 Convergent liquid phase syntheses of oligonucleotides BIOGEN MA INC. (US) 2025-08-05 US disclosed
EP-0164054-A1 Method for detection of polymorphic restriction sites and nucleic acid sequences CETUS CORPORATION (US) 1985-12-11 EP disclosed
EP-0130564-A1 Modified (80-113) beta interferons G.D. Searle & Co. (US) 1985-01-09 EP disclosed
EP-0130565-A1 Modified (115-145) beta interferons G.D. Searle & Co. (US) 1985-01-09 EP disclosed
EP-0130566-A1 Modified (1-28) beta interferons G.D. Searle & Co. (US) 1985-01-09 EP disclosed
EP-0068375-A2 Recombinant DNA techniques for the production of relaxin G.D. Searle & Co. (US) 1983-01-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND RNGTT, PPA1, PNP CA4 3126/4885AHR 4538/4885LTA4H 1374/4885
US-12378276-B2 Convergent liquid phase syntheses of oligonucleotides RTCB, RNGTT, POLR2H CA4 1773/4885AHR 4854/4885LTA4H 2451/4885
US-20260083759-A1 Combinations Comprising Psychedelics for the Treatment of Schizophrenia and Other Neuropsychiatric and Neurologic Disorders BDNF, NTRK2, GRIN2A CA4 4840/4885AHR 1671/4885LTA4H 3732/4885
US-20060009628-A1 MODIFIED OLIGONUCLEOTIDES FOR MISMATCH DISCRIMINATION MSH2, RNGTT, DCLRE1B CA4 3519/4885AHR 2142/4885LTA4H 4413/4885
US-12590330-B2 Methods for indexing samples and sequencing multiple polynucleotide templates POLRMT, SSBP1, MAVS CA4 4558/4885AHR 3013/4885LTA4H 4657/4885
US-20220304980-A1 METERED DOSING COMPOSITIONS AND METHODS OF USE OF PSYCHEDELIC COMPOUNDS PNMT, CRH, HTR5A CA4 3778/4885AHR 164/4885LTA4H 1870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.