Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13979638 | 1.00 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4656546 | 0.78 | GAA (0.50) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL13979631 | 0.78 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6675068 | 0.77 | ALDH1A1 (0.61) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL13915431 | 0.75 | RXRA (0.50) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4621752 | 0.75 | RXRA (0.50) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL28409911 | 0.75 | RXRA (0.50) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL28409564 | 0.75 | RXRA (0.50) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL10398562 | 0.70 | CASP3 (0.47) | ALDH1A1CASP3CA9GLSHTT | |
| SCHEMBL13979654 | 0.69 | GAA (0.42) | MAPTALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378439-B2 | Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride | USV, LTD. (IN) | 2008-05-27 | — | — | US | disclosed |
| US-20050159605-A1 | Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride | USV LIMITED (IN) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159605-A1 | Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride | PARK7, SNCA, TPH1 | MAPT 95/4885ALDH1A1 351/4885MEN1 3507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.