SCHEMBL465751

SCHEMBL465751

Cc1cc(C#N)cc2c(=O)oc(-c3cc(Br)nn3-c3ncccc3Cl)nc12

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.41
▸ CYP17A1 P05093 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ ELANE P08246 1/20 0.30
▸ PIM1 P11309 1/20 0.30
▸ CSNK2A2 P19784 1/20 0.30
▸ CSNK2B P67870 1/20 0.30
▸ PIM3 Q86V86 1/20 0.30
▸ PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29669886 1.00 DHODH (0.41) DHODHCYP17A1CYP1A2ELANEPIM1
SCHEMBL29975234 0.92 DHODH (0.38) DHODHPIM1CSNK2A2CSNK2BPIM3
SCHEMBL958594 0.91 DHODH (0.33) DHODHCYP17A1CYP1A2ELANEPIM1
SCHEMBL30234217 0.90 DHODH (0.33) DHODHCYP17A1CYP1A2ELANE
SCHEMBL15972086 0.90 DHODH (0.33) DHODHCYP17A1CYP1A2ELANE
SCHEMBL31059998 0.90 DHODH (0.33) DHODHCYP17A1CYP1A2ELANEPIM1
SCHEMBL29598524 0.89 DHODH (0.43) DHODHCYP17A1CYP1A2ELANE
SCHEMBL12528168 0.89 DHODH (0.43) DHODHCYP17A1CYP1A2ELANE
SCHEMBL21822337 0.89 DHODH (0.43) DHODHCYP17A1CYP1A2ELANE
SCHEMBL30560159 0.89 DHODH (0.43) DHODHCYP17A1CYP1A2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490492-A Solid state form of cyantraniliprole 安道麦马克西姆有限公司 2023-07-25 — — CN claimed
US-20230312508-A1 IMPROVED PROCESS FOR PREPARATION OF ANTHRANILAMIDES GSP CROP SCIENCE PRIVATE LIMITED (IN) 2023-10-05 — — US disclosed
EP-3632911-B1 METHOD FOR PREPARING ISOXAZINONE COMPOUND AND APPLICATION THEREOF ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD (CN) 2023-08-09 — — EP disclosed
CN-116490492-A Solid state form of cyantraniliprole 安道麦马克西姆有限公司 2023-07-25 — — CN disclosed
WO-2022149098-A1 PROCESS FOR PREPARATION OF INSECTICIDAL ANTHRANILAMIDES UPL LIMITED (IN) 2022-07-14 — — WO disclosed
US-11299499-B2 Preparation method and application of isoxazinone compounds Zhejiang Zhuji United Chemicals Co., Ltd. (CN) 2022-04-12 — — US disclosed
EP-3632905-B1 METHOD FOR PREPARING N-ACYL ORTHO-AMINOBENZAMIDE MAX RUDONG CHEMICALS CO LTD (CN) 2021-12-01 — — EP disclosed
CN-113166095-A Process for preparing anthranilamides UPL有限公司 2021-07-23 — — CN disclosed
US-10807967-B2 Method of preparing N-acyl anthranilamide MAX (RUDONG) CHEMICALS CO., LTD. (CN) 2020-10-20 — — US disclosed
CN-107033135-B Method for preparing isooxazinone compound and application thereof 浙江省诸暨合力化学对外贸易有限公司 2020-09-11 — — CN disclosed
US-7247647-B2 Cyano anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-24 — — US disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 — — WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 — — WO disclosed
EP-1771070-A1 MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-04-11 — — EP disclosed
US-20060241304-A1 Method for preparing fused oxazinones FMC CORPORATION 2006-10-26 — — US disclosed
WO-2006068669-A1 MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-29 — — WO disclosed
WO-2006055922-A2 ANTHRANILAMIDE INSECTICIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-05-26 — — WO disclosed
US-20060111403-A1 Cyano anthranilamide insecticides FMC CORPORATION 2006-05-25 — — US disclosed
EP-1599463-A1 CYANO ANTHRANILAMIDE INSECTICIDES E.I. du Pont de Nemours and Company (US) 2005-11-30 — — EP disclosed
WO-2004067528-A1 CYANO ANTHRANILAMIDE INSECTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-08-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111403-A1 Cyano anthranilamide insecticides C1S, C5, CBR3 DHODH 1074/4885CYP17A1 3340/4885CYP1A2 686/4885
US-11299499-B2 Preparation method and application of isoxazinone compounds NISCH, SI, DAO DHODH 240/4885CYP17A1 152/4885CYP1A2 481/4885
US-10807967-B2 Method of preparing N-acyl anthranilamide NAAA, PAM, HAAO DHODH 701/4885CYP17A1 2053/4885CYP1A2 1056/4885
US-20230312508-A1 IMPROVED PROCESS FOR PREPARATION OF ANTHRANILAMIDES NAAA, AADAC, CYCS DHODH 1635/4885CYP17A1 2228/4885CYP1A2 179/4885
US-20060241304-A1 Method for preparing fused oxazinones STS, CA5A, SQOR DHODH 912/4885CYP17A1 472/4885CYP1A2 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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