Chloroform

Chloroform

SCHEMBL4658908

CC(COC(=O)O)OC(=O)O.ClC(Cl)Cl

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15308 0.93 TSHR (0.37) TSHRALDH1A1
SCHEMBL15053822 0.93 TSHR (0.37) TSHRALDH1A1
SCHEMBL8727210 0.93 TSHR (0.37) TSHRALDH1A1
SCHEMBL748244 0.93 TSHR (0.37) TSHRALDH1A1
Ammonia Solution, Strong SCHEMBL9513085 0.91 TSHR (0.35) TSHRALDH1A1
Methane SCHEMBL2179835 0.91 TSHR (0.35) TSHRALDH1A1
Methyl Alcohol SCHEMBL9400635 0.91 TSHR (0.35) TSHRALDH1A1
SCHEMBL7262572 0.91 TSHR (0.35) TSHRALDH1A1
Fluoride SCHEMBL6427102 0.91 TSHR (0.35) TSHRALDH1A1
Ethane SCHEMBL10522900 0.91 TSHR (0.35) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240123010-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING AVENIR WELLNESS SOLUTIONS INC (US) 2024-04-18 US disclosed
US-11938160-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2024-03-26 US disclosed
US-11890310-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2024-02-06 US disclosed
US-11844763-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2023-12-19 US disclosed
US-20230085079-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2023-03-16 US disclosed
US-20220280582-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING SINDERBRAND LAW GROUP, PC 2022-09-08 US disclosed
US-11344591-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2022-05-31 US disclosed
US-11331358-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2022-05-17 US disclosed
US-20200246405-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CURE PHARMACEUTICAL HOLDING CORP. (US) 2020-08-06 US disclosed
US-20200246406-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CURE PHARMACEUTICAL HOLDING CORP. (US) 2020-08-06 US disclosed
US-6634575-B2 Birch bark processing and the isolation of natural products from birch bark REGENTS OF THE UNIVERSITY OF MINNESOTA 2003-10-21 US disclosed
US-20030109727-A1 Isolation of natural products from birch bark REGENTS OF THE UNIVERSITY OF MINNESOTA 2003-06-12 US disclosed
US-20020155177-A1 Process for extracting compounds from plants REGENTS OF THE UNIVERSITY OF MINNESOTA 2002-10-24 US disclosed
US-20020114853-A1 Process for extracting compounds from plants REGENTS OF THE UNIVERSITY OF MINNESOTA 2002-08-22 US disclosed
US-20020070167-A1 Birch bark processing and the isolation of natural products from birch bark REGENTS OF THE UNIVERSITY OF MINNESOTA 2002-06-13 US disclosed
EP-1206481-A2 BIRCH BARK PROCESSING AND THE ISOLATION OF NATURAL PRODUCTS FROM BIRCH BARK REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2002-05-22 EP disclosed
US-6392070-B1 Birch bark processing and the isolation of natural products from birch bark REGENTS OF THE UNIVERSITY OF MINNESOTA 2002-05-21 US disclosed
US-20020043577-A1 Birch bark processing and the isolation of natural products from birch bark REGENTS OF THE UNIVERSITY OF MINNESOTA 2002-04-18 US disclosed
WO-2002026343-A2 PROCESS FOR EXTRACTING COMPOUNDS FROM PLANTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2002-04-04 WO disclosed
WO-2001010885-A2 BIRCH BARK PROCESSING AND THE ISOLATION OF NATURAL PRODUCTS FROM BIRCH BARK REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2001-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844763-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-20230085079-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-20200246406-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-20200246405-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-11890310-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-20030109727-A1 Isolation of natural products from birch bark ALOX15, ALOX12, ALOX5 TSHR 4813/4885ALDH1A1 1473/4885
US-11344591-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-11331358-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-20220280582-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-20240123010-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-11938160-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 TSHR 4585/4885ALDH1A1 4647/4885
US-20020114853-A1 Process for extracting compounds from plants ATL3, NPEPPS, NAAA TSHR 4825/4885ALDH1A1 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.