SCHEMBL466338

SCHEMBL466338

N=C(N)NCCC(N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PMP22 Q01453 2/20 0.48
ALOX15 P16050 1/20 0.48
BLM P54132 1/20 0.48
KMT2A Q03164 1/20 0.48
GSR P00390 2/20 0.45
CYP1A2 P05177 2/20 0.45
GRM8 O00222 1/20 0.45
GRM6 O15303 1/20 0.45
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GRIK1 P39086 1/20 0.45
GRM5 P41594 1/20 0.45
GRIA1 P42261 1/20 0.45
GRIA2 P42262 1/20 0.45
GRIA3 P42263 1/20 0.45
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
GRIA4 P48058 1/20 0.45
GRIN1 Q05586 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574645 1.00 PMP22 (0.48) PMP22ALOX15BLMKMT2AGSR
SCHEMBL1527399 1.00 PMP22 (0.48) PMP22ALOX15BLMKMT2AGSR
Alanine SCHEMBL6762705 0.93 NOS3 (0.44) PMP22ALOX15BLMKMT2AGSR
Alanine SCHEMBL6762703 0.93 NOS3 (0.44) PMP22ALOX15BLMKMT2AGSR
Adipic Acid SCHEMBL8058451 0.89 BHMT (0.50) PMP22ALOX15BLMKMT2AGSR
Arginine SCHEMBL6374054 0.88 OTC (0.56) PMP22ALOX15BLMKMT2AGSR
Arginine SCHEMBL288132 0.88 OTC (0.56) PMP22ALOX15BLMKMT2AGSR
Arginine SCHEMBL2411547 0.88 OTC (0.56) PMP22ALOX15BLMKMT2AGSR
Arginine SCHEMBL7928810 0.88 OTC (0.56) PMP22ALOX15BLMKMT2AGSR
Arginine SCHEMBL1790 0.88 OTC (0.56) PMP22ALOX15BLMKMT2AGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 931 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091126-A1 AMINO ACID-MODIFIED LIPIDS FOR RNA DELIVERY UNIV MISSOURI (US) 2026-04-02 US claimed
EP-4702986-A1 POLYPEPTIDE AND USE THEREOF Biocells (Beijing) Biotech Co., Ltd. (CN) 2026-03-04 EP claimed
US-12540161-B2 Linkers BICYCLETX LIMITED (GB) 2026-02-03 US claimed
US-20260028375-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH ZUERICH (CH) 2026-01-29 US claimed
US-20250346589-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS UNIV ERASMUS MED CT ROTTERDAM (NL) 2025-11-13 US claimed
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
EP-4590670-A1 PLATFORM AND SCAFFOLD FOR FAP TARGETING AGENTS Erasmus University Rotterdam Medical Center (NL) 2025-07-30 EP claimed
US-20250171776-A1 NON-CANONICAL CELL-PENETRATING PEPTIDES FOR ANTISENSE OLIGOMER DELIVERY SAREPTA THERAPEUTICS, INC. (US) 2025-05-29 US claimed
EP-3833676-B1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH ZUERICH (CH) 2025-05-28 EP claimed
CN-120022230-A Peroxide hydrogel and preparation method thereof 千氧生物技术(上海)有限公司 2025-05-23 CN claimed
EP-0585412-B1 INCREASING BLOOD-BRAIN BARRIER PERMEABILITY WITH PERMEABILIZER PEPTIDES ALKERMES INC (US) 1999-07-07 EP claimed
EP-0561412-B1 Parathyroid hormone derivatives TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-02-03 EP claimed
EP-0885900-A2 Increasing blood-brain barrier permeability with permeabilizer peptide derivatives of bradykinin ALKERMES, INC. (US) 1998-12-23 EP claimed
WO-1998053051-A1 SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1998-11-26 WO claimed
WO-1998053050-A2 SHORT PEPTIDES WHICH SELECTIVELY MODULATE THE ACTIVITY OF SERINE/THREONINE KINASES THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1998-11-26 WO claimed
US-5686416-A BRADYKININ ANALOGUES; NONA-, DECA- AND POLYPEPTIDES ALKERMES, INC. (US) 1997-11-11 US claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
US-5506206-A ARGININE-PROLINE-HYDROXYPROLINE-GLYCINE-THIENYLALANINE-SERINE -(4-METHYL-TYROSINE)-ARGANINE OR A CONFORMATIONAL ANALOGUE, USED AS THERAPEUTICAL OR DIAGNOSTIC AGENTS ALKERMES, INC. (US) 1996-04-09 US claimed
EP-0585412-A1 INCREASING BLOOD-BRAIN BARRIER PERMEABILITY WITH PERMEABILIZER PEPTIDES ALKERMES, INC. (US) 1994-03-09 EP claimed
WO-1992018529-A1 INCREASING BLOOD-BRAIN BARRIER PERMEABILITY WITH PERMEABILIZER PEPTIDES ALKERMES, INC. (US) 1992-10-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346589-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS SSTR2, SSTR5, SSTR1 PMP22 4296/4885ALOX15 4502/4885BLM 3001/4885
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS ACE2, SARS1, TMPRSS2 PMP22 3755/4885ALOX15 4068/4885BLM 3124/4885
US-20260028375-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES PHAX, TPX2, MLX PMP22 3746/4885ALOX15 2769/4885BLM 541/4885
US-20250171776-A1 NON-CANONICAL CELL-PENETRATING PEPTIDES FOR ANTISENSE OLIGOMER DELIVERY MYOF, TNNC1, MTPN PMP22 460/4885ALOX15 2687/4885BLM 2089/4885
US-20260091126-A1 AMINO ACID-MODIFIED LIPIDS FOR RNA DELIVERY METTL16, SLC7A1, RNMT PMP22 3790/4885ALOX15 792/4885BLM 3778/4885
US-12540161-B2 Linkers ADM2, CDA, DCTD PMP22 3167/4885ALOX15 3617/4885BLM 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.