Sugi Predict

Sugi Predict / Compounds / SCHEMBL466415

SCHEMBL466415

SCHEMBL466415

CCc1cc(C)cc(CC)c1CC(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSK3B P49841 1/20 0.35
▸ TSHR P16473 3/20 0.33
▸ TPMT P51580 1/20 0.32
▸ ALDH1A1 P00352 4/20 0.32
▸ KDM4E B2RXH2 3/20 0.32
▸ HPGD P15428 3/20 0.32
▸ HTT P42858 2/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ PPARG P37231 1/20 0.32
▸ MAPK10 P53779 1/20 0.32
▸ NCOA2 Q15596 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ ALOX15 P16050 1/20 0.31
▸ ALOX12 P18054 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ PLA2G2A P14555 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3001741 0.84 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDL3MBTL1GABRA1
SCHEMBL509373 0.83 MEN1 (0.38) GSK3BTSHRALDH1A1KDM4EHTT
SCHEMBL509931 0.83 ALDH1A1 (0.36) GSK3BTSHRTPMTALDH1A1HPGD
SCHEMBL2429892 0.82 PTGDR2 (0.33) GSK3B
SCHEMBL510120 0.81 MAPT (0.46) TSHRTPMTALDH1A1KDM4EHPGD
Hydrochloric Acid SCHEMBL20740117 0.79 MAPT (0.45) TSHRTPMTALDH1A1KDM4EHPGD
SCHEMBL37165 0.78 KDM4E (0.40) TSHRTPMTALDH1A1KDM4EHPGD
SCHEMBL3081523 0.76 KDM4E (0.46) TSHRALDH1A1KDM4EHPGDGAA
SCHEMBL2167805 0.76 KMT2A (0.44) ALDH1A1KDM4EHPGDHTTL3MBTL1
SCHEMBL920912 0.75 P2RX7 (0.43) ALDH1A1HPGDL3MBTL1GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190119298-A1 FUSED 3-PHENYLTETRAMIC ACID DERIVATIVES HAVING HERBICIDAL ACTION BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-04-25 — — US disclosed
EP-3442978-A1 ANELLATED 3-PHENYL TETRAMIC ACID DERIVATIVES HAVING A HERBICIDAL EFFECT Bayer CropScience AG (DE) 2019-02-20 — — EP disclosed
US-9096533-B2 Pyridazinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-04 — — US disclosed
US-9096534-B2 Pyridazinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-04 — — US disclosed
US-9029295-B2 Pyridazinone compound and herbicide and noxious arthropod controlling agent comprising it SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-12 — — US disclosed
US-20150126738-A1 PYRIDAZINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2015-05-07 — — US disclosed
US-20150126739-A1 PYRIDAZINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2015-05-07 — — US disclosed
EP-2658845-B1 PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT SUMITOMO CHEMICAL CO (JP) 2015-02-25 — — EP disclosed
US-8962625-B2 Pyridazinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-24 — — US disclosed
EP-2658845-A1 PYRIDAZINONE COMPOUND AND HERBICIDE AND NOXIOUS ARTHROPOD CONTROLLING AGENT COMPRISING IT Sumitomo Chemical Company Limited (JP) 2013-11-06 — — EP disclosed
EP-1996557-B1 PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES SUMITOMO CHEMICAL CO (JP) 2010-03-03 — — EP disclosed
US-20090111696-A1 Pyridazinone Compound and Use Thereof as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 — — US disclosed
WO-2009035145-A2 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-19 — — WO disclosed
WO-2009035151-A2 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-19 — — WO disclosed
WO-2009035146-A2 HERBICIDAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-19 — — WO disclosed
US-20080318776-A1 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2008-12-25 — — US disclosed
US-20080318776-A1 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2008-12-25 — — US disclosed
US-20080318776-A1 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2008-12-25 — — US disclosed
EP-1996557-A1 PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES Sumitomo Chemical Company, Limited (JP) 2008-12-03 — — EP disclosed
WO-2007119434-A1 PYRIDAZINONE COMPOUND AND USE THEREOF AS HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126738-A1 PYRIDAZINONE COMPOUND AND USE THEREOF PDXK, PLPBP, PNPO GSK3B 798/4885TSHR 1592/4885TPMT 1011/4885
US-20150126739-A1 PYRIDAZINONE COMPOUND AND USE THEREOF PDXK, PLPBP, PNPO GSK3B 798/4885TSHR 1592/4885TPMT 1011/4885
US-20080318776-A1 2,6-Diethyl-4-Methylphenyl-Substituted Tetramic Acid Derivatives DDT, TET1, TET3 GSK3B 3223/4885TSHR 772/4885TPMT 209/4885
US-20190119298-A1 FUSED 3-PHENYLTETRAMIC ACID DERIVATIVES HAVING HERBICIDAL ACTION HPD, AGXT, AADAC GSK3B 2650/4885TSHR 1731/4885TPMT 1818/4885
US-20090111696-A1 Pyridazinone Compound and Use Thereof as herbicides PDXK, DDT, PLPBP GSK3B 943/4885TSHR 1568/4885TPMT 941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.