SCHEMBL466434

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL61590	0.87	GABRA1 (0.54)	GABRA1GABRB2ALDH1A1SMN1; SMN2LIPG
	SCHEMBL14176579	0.82	ALDH1A1 (0.34)	GABRA1GABRB2PTGS2ALDH1A1HSD17B10
	SCHEMBL830766	0.82	ALDH1A1 (0.34)	GABRA1GABRB2ALDH1A1HSD17B10TP53
	SCHEMBL61913	0.82	ALDH1A1 (0.50)	GABRA1GABRB2ALDH1A1HSD17B10LIPG
	SCHEMBL28221318	0.79	ALDH1A1 (0.48)	GABRA1GABRB2ALDH1A1HSD17B10LIPG
	SCHEMBL20694978	0.79	ALDH1A1 (0.48)	GABRA1GABRB2ALDH1A1HSD17B10LIPG
	SCHEMBL31200489	0.79	GABRA1 (0.52)	GABRA1GABRB2
	SCHEMBL24331100	0.79	GABRA1 (0.52)	GABRA1GABRB2ALDH1A1CYP3A4TSHR
	SCHEMBL24330450	0.79	RIPK1 (0.36)	GABRA1GABRB2ALDH1A1POLBLIPG
	SCHEMBL29515588	0.79	GABRA1 (0.52)	GABRA1GABRB2ALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.