Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1396422 | 1.00 | MGAM (0.42) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL13876099 | 0.84 | MGAM (0.41) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL10087903 | 0.83 | ALDH1A1 (0.44) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL22971403 | 0.83 | CYP1A2 (0.41) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL7814504 | 0.83 | MGAM (0.39) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL18127567 | 0.83 | LMNA (0.52) | GAAALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6900350 | 0.83 | ALDH1A1 (0.44) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL10860443 | 0.83 | ALDH1A1 (0.58) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL10087917 | 0.83 | MMP1 (0.47) | MGAMGAASIMGAM2SOAT1 | |
| SCHEMBL6898156 | 0.83 | TSHR (0.41) | ALDH1A1LMNAL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101838218-A | Ester compound and pharmaceutical use of the same | JAPAN TOBACCO INC | 2010-09-22 | — | — | CN | claimed |
| CN-1630629-A | Ester compound and medical use thereof | JAPAN TOBACCO INC (JP) | 2005-06-22 | — | — | CN | claimed |
| US-10710956-B2 | Process for the preparation of acrylate esters from alkyl lactates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190241495-A1 | PROCESS FOR THE PREPARATION OF ACRYLATE ESTERS FROM ALKYL LACTATES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-08-08 | — | — | US | disclosed |
| US-20170267639-A1 | Process for Synthesizing Oxidized Lactam Compounds | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-09-21 | — | — | US | disclosed |
| US-20160318869-A1 | Heterocyclic Compounds for the Treatment of Neurological and Psychological Disorders | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2016-11-03 | — | — | US | disclosed |
| CN-105378045-A | 1-isopropoxy-1-oxopropan-2-yl pivalate as perfuming ingredient | FIRMENICH & CIE | 2016-03-02 | — | — | CN | disclosed |
| US-20160009713-A1 | Prodrugs of Heteraromatic Compounds | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2016-01-14 | — | — | US | disclosed |
| US-8431576-B2 | Heterocyclic compounds for the treatment of neurological and psychological disorders | ALKERMES PHARMA IRELAND LIMITED (IE) | 2013-04-30 | — | — | US | disclosed |
| CN-101838218-A | Ester compound and pharmaceutical use of the same | JAPAN TOBACCO INC | 2010-09-22 | — | — | CN | disclosed |
| CN-1630629-B | Ester compound and medical use thereof | JAPAN TOBACCO INC | 2010-05-05 | — | — | CN | disclosed |
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-11-20 | — | — | US | disclosed |
| US-6586368-B1 | Benzofuran derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| US-6537948-B1 | Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| US-6410484-B1 | ACTIVE MATERIAL; CONTROLLING WEEDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6339155-B1 | Process for producing 3-phenyluracil compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-15 | — | — | US | disclosed |
| EP-1122244-A1 | Uracil compounds and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-1101761-A2 | Process for producing 3-phenyluracil compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1095935-A1 | 6-Hydroxy-5,6-dihydrouracils as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318869-A1 | Heterocyclic Compounds for the Treatment of Neurological and Psychological Disorders | GABBR1, GABBR2, GABRE | MGAM 2555/4885GAA 947/4885SI 881/4885 |
| US-20190241495-A1 | PROCESS FOR THE PREPARATION OF ACRYLATE ESTERS FROM ALKYL LACTATES | LDHA, LDHB, PDK4 | MGAM 189/4885GAA 342/4885SI 665/4885 |
| US-20170267639-A1 | Process for Synthesizing Oxidized Lactam Compounds | COASY, DHPS, OXA1L | MGAM 308/4885GAA 794/4885SI 356/4885 |
| US-10710956-B2 | Process for the preparation of acrylate esters from alkyl lactates | LDHA, LDHB, PDK4 | MGAM 189/4885GAA 342/4885SI 665/4885 |
| US-20030216258-A1 | Condensed heterocylic compounds and herbicides containing them as active ingredients | CBR3, CBR1, HAAO | MGAM 2073/4885GAA 3021/4885SI 3331/4885 |
| US-20160009713-A1 | Prodrugs of Heteraromatic Compounds | CYP2D6, CYP2B6, CYP3A4 | MGAM 2574/4885GAA 1176/4885SI 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.