Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678005 | 0.83 | FPR2 (0.43) | CCR5FPR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4678008 | 0.83 | FPR2 (0.43) | CCR5FPR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4801360 | 0.82 | FPR2 (0.37) | CCR5FPR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL1838649 | 0.80 | DRD2 (0.41) | CCR5FPR2CYP2C9OPRM1ALDH1A1 | |
| SCHEMBL4674483 | 0.80 | ALDH1A1 (0.45) | CCR5CYP2D6CYP2C19MAPTL3MBTL1 | |
| SCHEMBL3806769 | 0.79 | FPR2 (0.41) | CCR5FPR2OPRK1OGFRL1OPRM1 | |
| SCHEMBL4675598 | 0.79 | CYP3A4 (0.40) | CYP2D6OPRM1 | |
| SCHEMBL4734970 | 0.78 | LMNA (0.42) | CCR5FPR2CYP2D6LMNA | |
| SCHEMBL4678001 | 0.78 | FPR2 (0.42) | CCR5FPR2CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1835272 | 0.78 | OPRM1 (0.50) | CYP2D6CYP2C9OPRK1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |