Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 15/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3806769 | 0.81 | FPR2 (0.41) | LMNACCR5FPR2 | |
| SCHEMBL4678002 | 0.78 | CCR5 (0.42) | LMNACCR5CYP2D6FPR2 | |
| SCHEMBL1838649 | 0.76 | DRD2 (0.41) | CCR5FPR2KMT2AKCNH2 | |
| SCHEMBL4675598 | 0.74 | CYP3A4 (0.40) | CYP2D6 | |
| SCHEMBL4674483 | 0.74 | ALDH1A1 (0.45) | LMNACCR5CYP2D6MEN1KMT2A | |
| SCHEMBL4738085 | 0.73 | TNKS (0.42) | CCR5KMT2A | |
| SCHEMBL4734750 | 0.72 | DPP7 (0.37) | CYP2D6MEN1KMT2A | |
| SCHEMBL4730149 | 0.72 | HSD11B1 (0.41) | CYP2D6 | |
| SCHEMBL3670664 | 0.72 | CALCRL (0.46) | NPSR1 | |
| SCHEMBL1835272 | 0.72 | OPRM1 (0.50) | LMNACYP2D6KCNH2MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |