Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678008 | 0.85 | FPR2 (0.43) | FPR2CCR5OGFRL1POLBMAPT | |
| SCHEMBL4678005 | 0.85 | FPR2 (0.43) | FPR2CCR5OGFRL1POLBMAPT | |
| SCHEMBL4682261 | 0.80 | DRD2 (0.44) | FPR2CCR5OPRM1CYP2C9 | |
| SCHEMBL4674480 | 0.80 | ALDH1A1 (0.44) | CCR5MAPTCYP2D6CYP2C19 | |
| SCHEMBL4675596 | 0.79 | CYP3A4 (0.40) | OPRM1OPRK1 | |
| SCHEMBL4678002 | 0.78 | CCR5 (0.42) | FPR2CCR5OGFRL1POLBMAPT | |
| SCHEMBL4676160 | 0.78 | HSD11B1 (0.45) | POLB | |
| SCHEMBL3803735 | 0.78 | OPRM1 (0.49) | OPRM1OPRK1CYP2D6CYP2C9 | |
| SCHEMBL4674536 | 0.76 | PTGDR2 (0.35) | OPRM1OPRK1 | |
| SCHEMBL4681956 | 0.74 | OPRL1 (0.48) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |