Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | CCL5 | P13501 | 10/20 | 0.34 |
| ▸ | CCR5 | P51681 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690538 | 0.80 | CCL5 (0.36) | HCRTR1HCRTR2CCL5CCR5 | |
| SCHEMBL4692820 | 0.79 | CCL5 (0.35) | HCRTR1HCRTR2CCL5CCR5ALDH1A1 | |
| SCHEMBL4694116 | 0.76 | HCRTR2 (0.38) | HCRTR1HCRTR2CCR5 | |
| SCHEMBL4691519 | 0.76 | PLA2G10 (0.34) | MEN1KMT2AHCRTR1HCRTR2CCR5 | |
| SCHEMBL4690155 | 0.75 | MEN1 (0.38) | MEN1KMT2ACCL5CCR5ALDH1A1 | |
| SCHEMBL4694094 | 0.75 | CHRNB2 (0.44) | CCR5ALDH1A1 | |
| SCHEMBL4690489 | 0.75 | PKM (0.38) | KMT2ACCL5CCR5 | |
| SCHEMBL4694287 | 0.75 | CCR5 (0.37) | CCL5CCR5 | |
| SCHEMBL4693281 | 0.74 | CHRNB2 (0.43) | MEN1KMT2ACCR5 | |
| SCHEMBL4692781 | 0.73 | PKM (0.36) | MEN1KMT2ACCL5CCR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |