Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413461 | 0.79 | ALOX12 (0.51) | ALOX12LMNANPSR1TLR8ALDH1A1 | |
| SCHEMBL4700339 | 0.79 | MGLL (0.44) | ALDH1A1MAPTOPRM1KDM4EHCAR1 | |
| SCHEMBL5906196 | 0.77 | SMN1; SMN2 (0.42) | LMNAALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5906387 | 0.76 | MGLL (0.44) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL8599860 | 0.75 | TLR8 (0.49) | ALOX12LMNANPSR1TLR8ALDH1A1 | |
| SCHEMBL5973251 | 0.73 | CDK4 (0.53) | ALOX12LMNANPSR1TLR8ALDH1A1 | |
| SCHEMBL29833592 | 0.73 | CDK4 (0.53) | ALOX12LMNANPSR1TLR8ALDH1A1 | |
| SCHEMBL4700338 | 0.72 | HCAR1 (0.46) | ALOX12LMNANPSR1TLR8ALDH1A1 | |
| SCHEMBL13219469 | 0.71 | ALDH1A1 (0.54) | ALOX12LMNANPSR1ALDH1A1MEN1 | |
| SCHEMBL10460925 | 0.70 | LMNA (0.53) | ALOX12LMNANPSR1TLR8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468868-A | Process for the selective chlorination of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-one | FMC CORPORATION (US) | 1995-11-21 | — | — | US | claimed |
| EP-0974587-B1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEM IND CO (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-6077814-A | LOW PHYTOTOXICITY TO THE CROP PLANTS; SELECTIVE ACTIVITY | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0974587-A1 | 1-SUBSTITUTED 4-CARBAMOYL-1,2,4-TRIAZOL-5-ONE DERIVATIVES AND HERBICIDE | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-5468868-A | Process for the selective chlorination of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-one | FMC CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| US-5468868-A | Process for the selective chlorination of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-one | FMC CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| CN-1110683-A | Process for the selective chlorination of 4,5-dihydro-1-phenyl-1h-1,2,4-triazol-5-one | FMC CORP (US) | 1995-10-25 | — | — | CN | disclosed |