Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.35 |
| ▸ | CTSL | P07711 | 6/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701830 | 0.89 | CTSK (0.37) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4702622 | 0.88 | FYN (0.33) | CTSSCTSLCTSKCTSBHPGDS | |
| SCHEMBL4703269 | 0.87 | ATP4A (0.36) | CTSSCTSLCTSKPARP1 | |
| SCHEMBL4703612 | 0.82 | CTSS (0.34) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4701371 | 0.81 | CTSL (0.33) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4704688 | 0.80 | CTSL (0.33) | CTSSCTSLCTSKCTSBPARP1 | |
| SCHEMBL4704896 | 0.80 | CTSK (0.34) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4699887 | 0.79 | CTSS (0.34) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4703317 | 0.79 | HRH3 (0.35) | CTSSCTSLCTSKCTSB | |
| SCHEMBL4701965 | 0.79 | DHODH (0.34) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198982-A1 | Cathepsin cysteine protease inhibitors | MERCK CANADA INC. (CA) | 2004-10-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198982-A1 | Cathepsin cysteine protease inhibitors | CTSB, CTSS, CTSZ | CTSS 2/4885CTSL 8/4885CTSK 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.