Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 5/20 | 0.44 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759328 | 0.93 | RORB (0.43) | RORBRORCHTTPTGER4AKR1C3 | |
| SCHEMBL4708293 | 0.90 | RORB (0.40) | RORBRORCP2RX7 | |
| SCHEMBL4706958 | 0.87 | RORB (0.42) | RORBRORCPTGER4P2RX7 | |
| SCHEMBL4707594 | 0.86 | RORB (0.43) | RORBRORCHTTL3MBTL1PTGER4 | |
| SCHEMBL4709738 | 0.86 | RORB (0.42) | RORBRORCP2RX7 | |
| SCHEMBL4705301 | 0.86 | RORB (0.42) | RORBRORCP2RX7 | |
| SCHEMBL27538912 | 0.85 | RORB (0.44) | RORBRORCHTTL3MBTL1PTGER4 | |
| SCHEMBL4705879 | 0.85 | RORB (0.42) | RORBRORCHTTL3MBTL1PTGER4 | |
| SCHEMBL4705134 | 0.84 | RORB (0.45) | RORBRORCHTTTP53POLB | |
| SCHEMBL4708736 | 0.84 | RORB (0.49) | RORBRORCSMN1; SMN2MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |