Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 9/20 | 0.40 |
| ▸ | RORC | P51449 | 5/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759328 | 0.95 | RORB (0.43) | RORBRORCP2RX7TACR1GPBAR1 | |
| SCHEMBL4705134 | 0.92 | RORB (0.45) | RORBRORCP2RX7 | |
| SCHEMBL4706973 | 0.90 | RORB (0.44) | RORBRORCP2RX7 | |
| SCHEMBL27576469 | 0.89 | RORC (0.39) | RORBRORCGPR52P2RX7TACR1 | |
| SCHEMBL4708282 | 0.87 | RORB (0.40) | RORBRORC | |
| SCHEMBL4706981 | 0.85 | IDH1 (0.42) | RORBRORC | |
| SCHEMBL4708122 | 0.85 | RORB (0.39) | RORBRORCGPR52 | |
| SCHEMBL4705502 | 0.85 | RORB (0.39) | RORBRORCP2RX7TACR1GAA | |
| SCHEMBL4705301 | 0.84 | RORB (0.42) | RORBRORCGPR52P2RX7 | |
| SCHEMBL4709738 | 0.84 | RORB (0.42) | RORBRORCP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |