Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 3/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708480 | 0.87 | RORB (0.42) | RORBRPS6KB1KCNN4GRM2GRM4 | |
| SCHEMBL4706973 | 0.86 | RORB (0.44) | RORBP2RX7RORC | |
| SCHEMBL4759328 | 0.86 | RORB (0.43) | RORBP2RX7PTGDR2RORC | |
| SCHEMBL4705528 | 0.85 | RORB (0.43) | RORBRPS6KB1P2RX7GRM2RORC | |
| SCHEMBL4707066 | 0.85 | RORB (0.41) | RORBRPS6KB1P2RX7KCNN4GRM2 | |
| SCHEMBL4705134 | 0.85 | RORB (0.45) | RORBRPS6KB1P2RX7GRM4PTGDR2 | |
| SCHEMBL4708293 | 0.84 | RORB (0.40) | RORBP2RX7RORCGPR52 | |
| SCHEMBL4709738 | 0.84 | RORB (0.42) | RORBP2RX7PTGDR2RORC | |
| SCHEMBL4708736 | 0.84 | RORB (0.49) | RORBRPS6KB1P2RX7PTGDR2RORC | |
| SCHEMBL4706958 | 0.82 | RORB (0.42) | RORBP2RX7KCNN4RORCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |