Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 8/20 | 0.37 |
| ▸ | RORC | P51449 | 5/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.36 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4707207 | 0.92 | RORB (0.40) | IDH1RORBRORCTACR1PTGER4 | |
| SCHEMBL4708690 | 0.92 | RORB (0.40) | RORBRORCTACR1PTGER4 | |
| SCHEMBL4706783 | 0.91 | RORB (0.38) | IDH1RORBRORCTACR1PTGER4 | |
| SCHEMBL4705371 | 0.89 | IDH1 (0.43) | IDH1RORBRORCKDRGPBAR1 | |
| SCHEMBL4706229 | 0.89 | IDH1 (0.44) | IDH1RORBRORCKDRGPBAR1 | |
| SCHEMBL4707926 | 0.88 | P2RX7 (0.36) | IDH1RORBRORCP2RX7TACR1 | |
| SCHEMBL4707863 | 0.86 | IDH1 (0.44) | IDH1RORBRORCTACR1GPBAR1 | |
| SCHEMBL4707403 | 0.86 | IDH1 (0.42) | IDH1RORBRORCSLC2A1SLC2A3 | |
| SCHEMBL4709676 | 0.85 | RORB (0.46) | IDH1RORBRORCSLC2A1SLC2A3 | |
| SCHEMBL4707181 | 0.85 | RORB (0.40) | RORBRORCP2RX7TACR1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |