SCHEMBL472089

SCHEMBL472089

C=CCOC(=O)C1CC=CCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.43
TSHR P16473 4/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 4/20 0.40
ALOX15 P16050 2/20 0.40
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
ESR2 Q92731 1/20 0.36
CYP3A4 P08684 1/20 0.35
TP53 P04637 1/20 0.33
GAA P10253 3/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3784429 0.90 TSHR (0.40) MIFTSHRPOLBMAPK1ALDH1A1
SCHEMBL3780920 0.88 TSHR (0.46) TSHRPOLBMAPK1ALDH1A1KMT2A
SCHEMBL472054 0.86 MIF (0.39) MIFTSHRPOLBMAPK1ALDH1A1
SCHEMBL6869874 0.84 ALDH1A1 (0.38) MIFTSHRPOLBMAPK1ALDH1A1
SCHEMBL29046929 0.81 MIF (0.41) MIFALDH1A1ALOX15KMT2AHSD17B10
SCHEMBL11835168 0.80 MIF (0.44) MIFTSHRALDH1A1ALOX15KMT2A
SCHEMBL17862134 0.80 MIF (0.44) MIFTSHRALDH1A1ALOX15KMT2A
SCHEMBL719931 0.78
SCHEMBL423892 0.78 KMT2A (0.47) TSHRPOLBMAPK1ALDH1A1KMT2A
SCHEMBL472121 0.77 MAPT (0.44) MIFALDH1A1ALOX15KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8466303-B2 Process for production of epoxy compound SHOWA DENKO K.K. (JP) 2013-06-18 US claimed
US-20110009652-A1 PROCESS FOR PRODUCTION OF EPOXY COMPOUND SHOWA DENKO KK (JP) 2011-01-13 US claimed
EP-2261219-A1 PROCESS FOR PRODUCTION OF EPOXY COMPOUND Showa Denko K.K. (JP) 2010-12-15 EP claimed
US-7696366-B2 Production process of bifunctional epoxy monomer by selective oxidation of diolefin compound SHOWA DENKO K.K. (JP) 2010-04-13 US claimed
US-5194669-A Preparation of alkyl (alkoxycarbonylcyclohexyl) cyclohexenecarboxylates and dialkyl biphenyldicarboxylates EASTMAN KODAK COMPANY (US) 1993-03-16 US claimed
CN-115636712-A Preparation method of alkyl alkenyl cyclohexane 山东京博石油化工有限公司 2023-01-24 CN disclosed
EP-2566864-B1 PYRIDAZINONES AS GPR119 AGONISTS BOEHRINGER INGELHEIM INT (DE) 2014-09-03 EP disclosed
US-8772323-B2 Benzoxazole- and tetrahydrobenzoxazole-substituted pyridazinones as GPR119 agonists BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-07-08 US disclosed
EP-2270020-B1 EPOXY COMPOUND AND PROCESS FOR PRODUCING THE EPOXY COMPOUND SHOWA DENKO KK (JP) 2014-03-19 EP disclosed
US-8664414-B2 Process for producing epoxy compound SHOWA DENKO K.K. (JP) 2014-03-04 US disclosed
EP-2055708-B1 NOVEL EPOXY COMPOUND AND PRODUCTION PROCESS OF SAME SHOWA DENKO KK (JP) 2013-07-17 EP disclosed
US-20130172323-A1 PYRIDAZINONES AS GPR119 AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-07-04 US disclosed
US-20090030217-A1 PRODUCTION PROCESS OF BIFUNCTIONAL EPOXY MONOMER BY SELECTIVE OXIDATION OF DIOLEFIN COMPOUND SHOWA DENKO K.K. (JP) 2009-01-29 US disclosed
US-7381782-B2 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2008-06-03 US disclosed
EP-1891031-A2 PRODUCTION PROCESS OF BIFUNCTIONAL EPOXY MONOMER BY SELECTIVE OXIDATION OF DIOLEFIN COMPOUND Showa Denko K.K. (JP) 2008-02-27 EP disclosed
WO-2006123814-A2 PRODUCTION PROCESS OF BIFUNCTIONAL EPOXY MONOMER BY SELECTIVE OXIDATION OF DIOLEFIN COMPOUND SHOWA DENKO K.K. (JP) 2006-11-23 WO disclosed
US-20060258828-A1 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2006-11-16 US disclosed
EP-1655321-A1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME Zeon Corporation (JP) 2006-05-10 EP disclosed
US-5194669-A Preparation of alkyl (alkoxycarbonylcyclohexyl) cyclohexenecarboxylates and dialkyl biphenyldicarboxylates EASTMAN KODAK COMPANY (US) 1993-03-16 US disclosed
US-5194669-A Preparation of alkyl (alkoxycarbonylcyclohexyl) cyclohexenecarboxylates and dialkyl biphenyldicarboxylates EASTMAN KODAK COMPANY (US) 1993-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172323-A1 PYRIDAZINONES AS GPR119 AGONISTS GPR65, GPR119, GPR55 MIF 3416/4885TSHR 378/4885POLB 4071/4885
US-20110009652-A1 PROCESS FOR PRODUCTION OF EPOXY COMPOUND DUOX2, EPX, DUOX1 MIF 3949/4885TSHR 4326/4885POLB 326/4885
US-20090030217-A1 PRODUCTION PROCESS OF BIFUNCTIONAL EPOXY MONOMER BY SELECTIVE OXIDATION OF DIOLEFIN COMPOUND DUOX2, DUOX1, DDT MIF 1324/4885TSHR 4623/4885POLB 1588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.