Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722324 | 0.85 | L3MBTL1 (0.32) | TACR1AKR1B1LMNA | |
| SCHEMBL4720655 | 0.75 | NTRK1 (0.34) | LMNANTRK1 | |
| SCHEMBL4720084 | 0.73 | NAMPT (0.33) | TACR1LMNANTRK1 | |
| SCHEMBL4719909 | 0.71 | TRPV1 (0.35) | TACR1LMNA | |
| SCHEMBL4723705 | 0.69 | TRPV1 (0.30) | — | |
| SCHEMBL4723153 | 0.69 | NTRK1 (0.33) | LMNANTRK1 | |
| SCHEMBL4721659 | 0.69 | RIOK2 (0.35) | — | |
| SCHEMBL4724242 | 0.68 | SLC40A1 (0.35) | TACR1 | |
| SCHEMBL4720511 | 0.68 | SLC40A1 (0.35) | TACR1 | |
| SCHEMBL4720512 | 0.68 | SLC40A1 (0.35) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |