Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64962 | 0.91 | POLB (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL6814509 | 0.87 | POLB (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL11921516 | 0.84 | THRB (0.55) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL22566492 | 0.83 | THRB (0.53) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL5077422 | 0.82 | THRB (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL17036777 | 0.82 | POLB (0.58) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL148322 | 0.82 | SMN1; SMN2 (0.56) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL345074 | 0.81 | POLB (0.42) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL10457799 | 0.80 | THRB (0.50) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL17036971 | 0.79 | POLB (0.63) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2716276-B1 | Kit and method for indirect chair-side production of composite inlays | VOCO GMBH (DE) | 2019-04-24 | — | — | EP | claimed |
| EP-2628476-B1 | FILLER CONTAINING COMPOSITION AND PROCESS FOR PRODUCTION AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2018-03-28 | — | — | EP | claimed |
| US-9833387-B2 | Kit and method for indirect chairside production of composite inlays | VOCO GMBH (DE) | 2017-12-05 | — | — | US | claimed |
| EP-2374444-B1 | Dental covering material | VOCO GMBH (DE) | 2017-03-01 | — | — | EP | claimed |
| US-20140138864-A1 | KIT AND METHOD FOR INDIRECT CHAIRSIDE PRODUCTION OF COMPOSITE INLAYS | VOCO GMBH (DE) | 2014-05-22 | — | — | US | claimed |
| EP-2628476-A1 | Filler containing Composition and Process for Production and Use thereof | 3M Innovative Properties Company (US) | 2013-08-21 | — | — | EP | claimed |
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | claimed |
| US-20240189195-A1 | DENTAL POLYMERIZABLE COMPOSITION | GC CORPORATION (JP) | 2024-06-13 | — | — | US | disclosed |
| US-11998417-B2 | Process for producing a surface-modified dental article | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-06-04 | — | — | US | disclosed |
| EP-4316452-A1 | POLYMERIZABLE DENTAL COMPOSITION | GC Corporation (JP) | 2024-02-07 | — | — | EP | disclosed |
| US-20230270630-A1 | COMPOSITION FOR DENTAL ATTACHMENT | KURARAY NORITAKE DENTAL INC. (JP) | 2023-08-31 | — | — | US | disclosed |
| EP-4035649-B1 | DENTAL ADHESIVE COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-07-26 | — | — | EP | disclosed |
| US-20230225829-A1 | PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-07-20 | — | — | US | disclosed |
| US-20030064102-A1 | Antimicrobial Composition | NAKATSUKA KAZUMITSU (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1287805-A1 | Dental adhesive composition | GC Corporation (JP) | 2003-03-05 | — | — | EP | disclosed |
| EP-1285947-A1 | ANTIMICROBIAL COMPOSITION | KURARAY CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-6512068-B1 | Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of | KURARAY CO., LTD. (JP) | 2003-01-28 | — | — | US | disclosed |
| EP-1057468-A1 | Adhesive composition and method for producing it | KURARAY CO., LTD. (JP) | 2000-12-06 | — | — | EP | disclosed |
| US-4918136-A | CURABLE MIXTURE OF VINYL MONOMER WITH ACIDIC GROUP, FILLER, POLYMERIZATION PROMOTER, ASCORBIC ACID; DENTISTRY | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0335645-A2 | Adhesive composition | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270630-A1 | COMPOSITION FOR DENTAL ATTACHMENT | ITGA1, ITGA2, PPA1 | POLB 2433/4885APEX1 194/4885HTT 2516/4885 |
| US-20030064102-A1 | Antimicrobial Composition | AAAS, H1-0, H1-10 | POLB 149/4885APEX1 890/4885HTT 958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.