Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | INPPL1 | O15357 | 3/20 | 0.35 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472594 | 0.91 | POLB (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL6814509 | 0.87 | POLB (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL11921516 | 0.84 | THRB (0.55) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL22566492 | 0.83 | THRB (0.53) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL5077422 | 0.82 | THRB (0.44) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL17036777 | 0.82 | POLB (0.58) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL148322 | 0.82 | SMN1; SMN2 (0.56) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL27245459 | 0.81 | NPC1 (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL10457799 | 0.80 | THRB (0.50) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL17036971 | 0.79 | POLB (0.63) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 610 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552956-B2 | Photopolymerizable type dental surface coating composition | SHOFU INC. (JP) | 2026-02-17 | — | — | US | claimed |
| EP-4488243-A1 | ACID-STABLE GLASS FILLERS AND SELF-ADHESIVE DENTAL COMPOSITE CEMENTS CONTAINING SAME HAVING GOOD TRANSPARENCY | Ivoclar Vivadent AG (LI) | 2025-01-08 | — | — | EP | claimed |
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | claimed |
| US-20240158614-A1 | STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY | IVOCLAR VIVADENT AG (LI) | 2024-05-16 | — | — | US | claimed |
| EP-4356893-A1 | STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY | Ivoclar Vivadent AG (LI) | 2024-04-24 | — | — | EP | claimed |
| US-20240099942-A1 | RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES | IVOCLAR VIVADENT AG (LI) | 2024-03-28 | — | — | US | claimed |
| EP-4331557-A1 | RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES | Ivoclar Vivadent AG (LI) | 2024-03-06 | — | — | EP | claimed |
| US-11712404-B2 | Methacrylamide adhesive systems | UNIV OREGON HEALTH & SCIENCE (US) | 2023-08-01 | — | — | US | claimed |
| EP-4205724-A1 | SELF-ADHESIVE DENTAL COMPOSITE CEMENTS WITH GOOD TRANSPARENCY BASED ON ACID-TREATED FILLERS | Ivoclar Vivadent AG (LI) | 2023-07-05 | — | — | EP | claimed |
| EP-4205723-A1 | HIGH TRANSPARENCY, SULPHATE-CONTAINING OR PHOSPHATE-CONTAINING DENTAL SELF-ADHERING COMPOSITE | Ivoclar Vivadent AG (LI) | 2023-07-05 | — | — | EP | claimed |
| US-20130090404-A1 | Dental materials with improved hydrolysis stability based on phthalic acid monomers | IVOCLAR VIVADENT AG (LI) | 2013-04-11 | — | — | US | claimed |
| US-8329845-B2 | Divided redox-curing type composition | KURARAY NORITAKE DENTAL INC. (JP) | 2012-12-11 | — | — | US | claimed |
| US-20120093741-A1 | DENTAL MASKING COMPOUND | VOCO GMBH (DE) | 2012-04-19 | — | — | US | claimed |
| EP-1749513-B1 | Photopolymerisable dental material with bisacylphosphine oxides as initiator | IVOCLAR VIVADENT AG (LI) | 2009-03-04 | — | — | EP | claimed |
| EP-1508321-B1 | Dental adhesive composition | DENTSPLY SANKIN K K (JP) | 2007-05-23 | — | — | EP | claimed |
| US-20050054749-A1 | Dental adhesive composition | DENTSPLY-SANKIN K.K. (JP) | 2005-03-10 | — | — | US | claimed |
| EP-1508321-A1 | Dental adhesive composition | DENTSPLY-SANKIN K.K. (JP) | 2005-02-23 | — | — | EP | claimed |
| US-5733949-A | Antimicrobial adhesive composition for dental uses | KURARAY CO., LTD. (JP) | 1998-03-31 | — | — | US | claimed |
| US-5321053-A | Curable mixture of vinyl monomer containing acidic group and photoinitiator | KURARAY CO., LTD. (JP) | 1994-06-14 | — | — | US | claimed |
| US-4259075-A | Method of filling a tooth cavity | KURARAY CO., LTD. (JP) | 1981-03-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | POLB 567/4885APEX1 1261/4885HTT 698/4885 |
| US-11712404-B2 | Methacrylamide adhesive systems | ECPAS, CAD, ILK | POLB 1284/4885APEX1 564/4885HTT 1604/4885 |
| US-20240099942-A1 | RADICALLY POLYMERIZABLE COMPOSITION COMPRISING A REDOX INITIATOR SYSTEM BASED ON DIHYDROPYRIDINES | TAS1R1, TAS2R1, TAS2R41 | POLB 264/4885APEX1 63/4885HTT 1959/4885 |
| US-12552956-B2 | Photopolymerizable type dental surface coating composition | CDH1, DCLRE1A, ITGA1 | POLB 1135/4885APEX1 241/4885HTT 3658/4885 |
| US-20130090404-A1 | Dental materials with improved hydrolysis stability based on phthalic acid monomers | RCOR1, SMC4, RER1 | POLB 1695/4885APEX1 1404/4885HTT 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.