SCHEMBL472620

SCHEMBL472620

O=[N+]([O-])Nc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472625 0.85 LMNA (0.42) CA1
SCHEMBL472651 0.84 CA1 (0.31) CA1CA2
SCHEMBL5008771 0.81 USP2 (0.45)
SCHEMBL1610490 0.81 NISCH (0.37) CA1CA2
SCHEMBL472288 0.81 MAPT (0.37)
SCHEMBL13299434 0.80 BACE1 (0.34) CA1CA2
SCHEMBL737953 0.79 NPC1 (0.35) CA1CA2
SCHEMBL472629 0.79 MAPT (0.34) CA1CA2
SCHEMBL1795659 0.79 ALOX12 (0.33) CA1CA2
SCHEMBL739419 0.79 USP2 (0.32) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785485-B2 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-22 US disclosed
EP-2412239-B1 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL CO (JP) 2014-04-16 EP disclosed
EP-2647285-A2 Pest control composition Sumitomo Chemical Company, Limited (JP) 2013-10-09 EP disclosed
EP-2601837-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Company, Limited (JP) 2013-06-12 EP disclosed
EP-2601835-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-06-12 EP disclosed
EP-2601838-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-06-12 EP disclosed
EP-2601836-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Company Limited (JP) 2013-06-12 EP disclosed
US-20130137682-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130131083-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131115-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131118-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131117-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131116-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20120035218-A1 PEST CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
US-20120029038-A1 ANIMAL ECTOPARASITE-CONTROLLING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-02 US disclosed
EP-2412239-A1 Animal ectoparasite-controlling agent Sumitomo Chemical Company, Limited (JP) 2012-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130137682-A1 PEST CONTROL COMPOSITION H1-4, HRH4, CHRM2 CA1 989/4885CA2 742/4885
US-20130131115-A1 PEST CONTROL COMPOSITION HRH2, HRH4, HRH1 CA1 1176/4885CA2 1092/4885
US-20130131118-A1 PEST CONTROL COMPOSITION H1-4, H1-10, H1-0 CA1 1094/4885CA2 1210/4885
US-20130131116-A1 PEST CONTROL COMPOSITION H1-4, H1-10, H1-0 CA1 870/4885CA2 1051/4885
US-20120029038-A1 ANIMAL ECTOPARASITE-CONTROLLING AGENT H1-3, HRH4, EEF1A1 CA1 1006/4885CA2 636/4885
US-20130131083-A1 PEST CONTROL COMPOSITION H1-4, H1-3, H1-0 CA1 1406/4885CA2 1614/4885
US-20130131117-A1 PEST CONTROL COMPOSITION H1-4, H1-0, H1-2 CA1 1266/4885CA2 1302/4885
US-20120035218-A1 PEST CONTROL COMPOSITION CTRL, CYP4F3, CYP4B1 CA1 1471/4885CA2 1171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.