SCHEMBL737953

SCHEMBL737953

Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1[N+](=O)[O-]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
USP2 O75604 1/20 0.34
TDP1 Q9NUW8 2/20 0.32
MAPT P10636 3/20 0.32
LMNA P02545 2/20 0.32
HTT P42858 1/20 0.32
AR P10275 4/20 0.31
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472629 0.92 MAPT (0.34) NPC1RAB9AMEN1KMT2AUSP2
Ammonia Solution, Strong SCHEMBL27964641 0.91 MAPT (0.33) NPC1RAB9AMEN1KMT2AUSP2
SCHEMBL1795659 0.88 ALOX12 (0.33) USP2MAPTARHPGDCA1
SCHEMBL472625 0.88 LMNA (0.42) USP2MAPTLMNAHTTAR
SCHEMBL472288 0.88 MAPT (0.37) MEN1KMT2AUSP2TDP1MAPT
SCHEMBL14046760 0.87 MAPT (0.33) NPC1RAB9AMEN1KMT2AUSP2
SCHEMBL472676 0.86 NCOA1 (0.33) USP2MAPTLMNAHTTSMN1; SMN2
SCHEMBL739419 0.86 USP2 (0.32) USP2MAPTLMNAHTTCA1
SCHEMBL1468064 0.85 RECQL (0.37) TDP1MAPTHTTHPGDCA1
SCHEMBL3116206 0.84 VCAM1 (0.44) USP2TDP1MAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120211150-A1 Method of Orienting A Polyester Film CRYOVAC, INC. 2012-08-23 US claimed
US-20230355590-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE NISSAN CHEMICAL CORPORATION (JP) 2023-11-09 US disclosed
US-10874645-B2 Isoxazoline-substituted benzamide compound and pesticide NISSAN CHEMICAL CORPORATION (JP) 2020-12-29 US disclosed
EP-3426491-B1 MULTILAYER FILM FOR VACUUM SKIN PACKAGING, METHOD OF PACKAGING AND PACKAGES OBTAINED THEREWITH CRYOVAC LLC (US) 2020-12-02 EP disclosed
US-20200155511-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE NISSAN CHEMICAL CORPORATION (JP) 2020-05-21 US disclosed
US-10639866-B2 Multilayer film for vacuum skin packaging, method of packaging and packages obtained therewith CRYOVAC, LLC (US) 2020-05-05 US disclosed
US-10596157-B2 Isoxazoline-substituted benzamide compound and pesticide NISSAN CHEMICAL CORPORATION (JP) 2020-03-24 US disclosed
US-20190030857-A1 MULTILAYER FILM FOR VACUUM SKIN PACKAGING, METHOD OF PACKAGING AND PACKAGES OBTAINED THEREWITH CRYOVAC, INC. (US) 2019-01-31 US disclosed
EP-3426491-A1 MULTILAYER FILM FOR VACUUM SKIN PACKAGING, METHOD OF PACKAGING AND PACKAGES OBTAINED THEREWITH Cryovac, Inc. (US) 2019-01-16 EP disclosed
EP-2185359-B1 DUAL OVENABLE VACUUM SKIN PACKAGED SEALED CONTAINER COMPRISING A RECEPTACLE CONTAINING A FOOD PRODUCT AND A SEALED THERMOFORMABLE POLYESTER FILM LID DUPONT TEIJIN FILMS US LP (US) 2019-01-02 EP disclosed
US-7662972-B2 Isoxazoline-substituted benzamide compound and pesticide NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-02-16 US disclosed
US-20100003377-A1 POLYESTER FILM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2010-01-07 US disclosed
US-20090312330-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-12-17 US disclosed
EP-2077943-A1 HEAT-SEALABLE COMPOSITE POLYESTER FILM Dupont Teijin Films U.S. Limited Partnership (US) 2009-07-15 EP disclosed
WO-2009032627-A2 DUAL OVENABLE FOOD PACKAGE HAVING A THERMOFORMABLE POLYESTER FILM LID DUPONT TEIJIN FILMS U.S. LIMITED PARTERSHIP (US) 2009-03-12 WO disclosed
EP-1984177-A1 POLYESTER FILM Dupont Teijin Films U.S. Limited Partnership (US) 2008-10-29 EP disclosed
WO-2008053205-A1 HEAT-SEALABLE COMPOSITE POLYESTER FILM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2008-05-08 WO disclosed
WO-2007093798-A1 POLYESTER FILM DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (US) 2007-08-23 WO disclosed
US-20070066617-A1 Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-22 US disclosed
EP-1731512-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT Nissan Chemical Industries, Ltd. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355590-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE HDAC7, ACHE, BRDT NPC1 3008/4885RAB9A 1269/4885MEN1 3896/4885
US-10596157-B2 Isoxazoline-substituted benzamide compound and pesticide CHRM3, C3AR1, C9 NPC1 2655/4885RAB9A 2580/4885MEN1 1926/4885
US-20090312330-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE ATM, CHRM1, NAT1 NPC1 761/4885RAB9A 602/4885MEN1 1887/4885
US-10874645-B2 Isoxazoline-substituted benzamide compound and pesticide C3AR1, C5, C9 NPC1 2937/4885RAB9A 2710/4885MEN1 1558/4885
US-20070066617-A1 Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly CHRM1, DDT, ATM NPC1 2291/4885RAB9A 214/4885MEN1 1665/4885
US-20200155511-A1 ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE C3AR1, C5, C9 NPC1 2937/4885RAB9A 2710/4885MEN1 1558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.