SCHEMBL472676

SCHEMBL472676

CCc1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1[N+](=O)[O-]

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
PDK1 Q15118 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10282199 0.94 NCOA1 (0.31) NCOA1NCOA3PDK1USP2LMNA
SCHEMBL3120927 0.91 USP2 (0.31) USP2LMNAMAPTHTT
SCHEMBL3112584 0.91 USP2 (0.31) USP2LMNAMAPTHTT
SCHEMBL27964626 0.90 USP2 (0.30) USP2LMNAMAPTHTT
SCHEMBL3123196 0.88 PTGS2 (0.33) LMNAMAPTHTTCA1CA2
SCHEMBL472629 0.88 MAPT (0.34) USP2LMNAMAPTHTTHPGD
SCHEMBL472288 0.88 MAPT (0.37) NCOA1NCOA3USP2LMNAMAPT
SCHEMBL472625 0.88 LMNA (0.42) USP2LMNAMAPTHTTHPGD
Ammonia Solution, Strong SCHEMBL27964641 0.87 MAPT (0.33) USP2LMNAMAPTHTTHPGD
SCHEMBL737953 0.86 NPC1 (0.35) USP2LMNAMAPTHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785485-B2 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-22 US disclosed
US-8785485-B2 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-22 US disclosed
US-8785485-B2 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-22 US disclosed
EP-2412239-B1 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL CO (JP) 2014-04-16 EP disclosed
EP-2647285-A2 Pest control composition Sumitomo Chemical Company, Limited (JP) 2013-10-09 EP disclosed
US-8507514-B2 Hydrazide compound and use of the same in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-13 US disclosed
US-8507514-B2 Hydrazide compound and use of the same in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-13 US disclosed
EP-2601836-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Company Limited (JP) 2013-06-12 EP disclosed
EP-2601837-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Company, Limited (JP) 2013-06-12 EP disclosed
EP-2601838-A1 PEST CONTROL COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-06-12 EP disclosed
EP-2412239-A1 Animal ectoparasite-controlling agent Sumitomo Chemical Company, Limited (JP) 2012-02-01 EP disclosed
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed
EP-2311817-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-20 EP disclosed
EP-2311816-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-20 EP disclosed
EP-2308858-A1 Isoxazoline Compounds and their Use in Pest Control Sumitomo Chemical Company, Limited (JP) 2011-04-13 EP disclosed
US-20100137372-A1 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100137372-A1 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
EP-2139874-A2 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2010-01-06 EP disclosed
WO-2008126665-A2 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137372-A1 ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL CYP4X1, PRDX5, PRDX1 NCOA1 2986/4885NCOA3 3545/4885PDK1 1255/4885
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL H1-4, H1-2, H1-0 NCOA1 1873/4885NCOA3 2928/4885PDK1 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.