Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472629 | 0.99 | MAPT (0.34) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL14046760 | 0.94 | MAPT (0.33) | MAPTSMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL737953 | 0.91 | NPC1 (0.35) | MAPTSMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL472625 | 0.89 | LMNA (0.42) | MAPTSMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL472288 | 0.89 | MAPT (0.37) | MAPTALDH1A1LMNAHTTUSP2 | |
| SCHEMBL472676 | 0.87 | NCOA1 (0.33) | MAPTSMN1; SMN2LMNAHTTUSP2 | |
| SCHEMBL739419 | 0.87 | USP2 (0.32) | MAPTLMNAHTTUSP2CA1 | |
| SCHEMBL3116206 | 0.85 | VCAM1 (0.44) | MAPTSMN1; SMN2LMNAHTTUSP2 | |
| SCHEMBL19723063 | 0.85 | USP2 (0.31) | MAPTLMNAHTTUSP2 | |
| SCHEMBL1795659 | 0.85 | ALOX12 (0.33) | MAPTUSP2HPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101652354-B | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG | 2014-06-18 | — | — | CN | disclosed |