Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726489 | 0.89 | LMNA (0.47) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL4727067 | 0.89 | TP53 (0.44) | GFERLMNASMN1; SMN2HRH3DRD3 | |
| SCHEMBL4729811 | 0.89 | ALDH1A1 (0.50) | LMNAHRH3MEN1KMT2ADRD3 | |
| SCHEMBL4779866 | 0.88 | DRD3 (0.49) | LMNAMEN1KMT2ADRD3L3MBTL1 | |
| SCHEMBL4726498 | 0.87 | ALDH1A1 (0.44) | LMNAMEN1KMT2ADRD3POLB | |
| SCHEMBL4728012 | 0.86 | CES1 (0.48) | LMNASMN1; SMN2DRD3MOGAT2MGAT2 | |
| SCHEMBL4725768 | 0.85 | MAPT (0.51) | LMNASMN1; SMN2KMT2ADRD3ALDH1A1 | |
| SCHEMBL4778150 | 0.85 | PGR (0.50) | LMNADRD3ALDH1A1MAPT | |
| SCHEMBL4727610 | 0.84 | UCHL1 (0.51) | LMNASMN1; SMN2MEN1KMT2ADRD3 | |
| SCHEMBL4726510 | 0.84 | CNR2 (0.49) | LMNAMEN1KMT2ADRD3MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008026046-A1 | MORPHOLINE D3 DOPAMINE ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |