SCHEMBL472759

SCHEMBL472759

CCCCCCCc1cc(=O)c2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSV O60911 4/20 1.00
CTSL P07711 4/20 1.00
GHSR Q92847 3/20 0.68
HSD17B10 Q99714 3/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
GAA P10253 2/20 0.52
PARP1 P09874 1/20 0.51
GPR84 Q9NQS5 5/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21065454 1.00 CTSV (1.00) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL26993704 1.00 CTSV (1.00) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL29367405 1.00 CTSV (1.00) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL30472916 1.00 CTSV (1.00) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL25422114 1.00 CTSV (1.00) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL25424145 1.00 CTSV (1.00) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL30913016 1.00 CTSV (1.00) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL29411985 1.00 CTSV (1.00) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL2821600 0.98 CTSV (0.97) CTSVCTSLGHSRHSD17B10KDM4E
SCHEMBL7835926 0.94 CTSV (0.88) CTSVCTSLGHSRHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230184759-A1 IN VITRO METHOD FOR DETECTION OF INFECTIONS CAUSED BY PSEUDOMONAS AERUGINOSA CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2023-06-15 US claimed
EP-4126820-A1 IN VITRO METHOD FOR DETECTION OF INFECTIONS CAUSED BY PSEUDOMONAS AERUGINOSA Consejo Superior De Investigaciones Científicas (ES) 2023-02-08 EP claimed
WO-2021198064-A1 IN VITRO METHOD FOR DETECTION OF INFECTIONS CAUSED BY PSEUDOMONAS AERUGINOSA CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2021-10-07 WO claimed
US-20190270909-A1 CONTROLLED RELEASE OF WATER-SOLUBLE AGENTS THE SECANT GROUP, LLC 2019-09-05 US claimed
US-10329448-B2 Method of making coated articles THE SECANT GROUP, LLC (US) 2019-06-25 US claimed
US-20160251540-A1 METHOD OF MAKING COATED ARTICLES THE SECANT GROUP, LLC 2016-09-01 US claimed
US-20260138981-A1 DIHYDROFOLATE REDUCTASE INHIBITORS FOR ANTI-BIOTIC RESISTANT INFECTIONS THE TRUSTEES OF PRINCETON UNIV (US) 2026-05-21 US disclosed
EP-4702981-A1 TARGETED ANTIBACTERIAL TREATMENT Københavns Universitet (DK) 2026-03-04 EP disclosed
WO-2024077235-A9 DIHYDROFOLATE REDUCTASE INHIBITORS FOR ANTI-BIOTIC RESISTANT INFECTIONS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2024-06-27 WO disclosed
CN-118063452-A Benzothiazole or benzoxazole derivative and preparation method and application thereof 山东大学 2024-05-24 CN disclosed
EP-4365928-A2 SPECTROMETRIC ANALYSIS OF MICROBES Micromass UK Limited (GB) 2024-05-08 EP disclosed
WO-2024077235-A2 DIHYDROFOLATE REDUCTASE INHIBITORS FOR ANTI-BIOTIC RESISTANT INFECTIONS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2024-04-11 WO disclosed
CN-115477610-B Preparation method of C-3 perfluoroalkyl 4-quinolinone compound 河北农业大学 2024-03-15 CN disclosed
US-7371779-B2 Synergistic compositions of N-acylhomoserine lactones and 4-quinolones THE SECRETARY OF STATE FOR DEFENSE SCIENCE AND TECHNOLOGY (GB) 2008-05-13 US disclosed
EP-1349550-B1 SUBSTITUTED-4-QUINOLONES FOR THE TREATMENT OF AUTOIMMUNE DISEASES SECR DEFENCE (GB) 2006-06-14 EP disclosed
EP-1404315-B1 SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES UNIV NOTTINGHAM (GB) 2004-11-03 EP disclosed
US-20040198978-A1 Synergistic compositions of n-acylhomoserine lactones and 4-quinolones THE SECRETARY OF STATE FOR DEFENCE (GB) 2004-10-07 US disclosed
US-20040082579-A1 Immunosuppressant THE SECRETARY OF STATE FOR DEFENCE (GB) 2004-04-29 US disclosed
EP-1404315-A1 SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES THE UNIVERSITY OF NOTTINGHAM (GB) 2004-04-07 EP disclosed
WO-2003004017-A1 SYNERGISTIC COMPOSITIONS OF N-ACYLHOMOSERINE LACTONES AND 4-QUINOLONES THE UNIVERSITY OF NOTTINGHAM (GB) 2003-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230184759-A1 IN VITRO METHOD FOR DETECTION OF INFECTIONS CAUSED BY PSEUDOMONAS AERUGINOSA QSOX1, QARS1, CD47 CTSV 4321/4885CTSL 3138/4885GHSR 1122/4885
US-10329448-B2 Method of making coated articles SGMS2, SGMS1, RHOA CTSV 4301/4885CTSL 3904/4885GHSR 2351/4885
US-20260138981-A1 DIHYDROFOLATE REDUCTASE INHIBITORS FOR ANTI-BIOTIC RESISTANT INFECTIONS DHFR, CBR1, DHRS9 CTSV 3677/4885CTSL 1324/4885GHSR 1425/4885
US-20160251540-A1 METHOD OF MAKING COATED ARTICLES SGMS2, SGMS1, RHOA CTSV 4301/4885CTSL 3904/4885GHSR 2351/4885
US-20040082579-A1 Immunosuppressant CCR6, CCR1, CCR8 CTSV 3955/4885CTSL 4059/4885GHSR 737/4885
US-20190270909-A1 CONTROLLED RELEASE OF WATER-SOLUBLE AGENTS ADH1A, ADH1C, MLEC CTSV 3794/4885CTSL 2176/4885GHSR 255/4885
US-20040198978-A1 Synergistic compositions of n-acylhomoserine lactones and 4-quinolones CBR3, CBR1, CNR1 CTSV 4696/4885CTSL 3582/4885GHSR 623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.