Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMBS | P08397 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727722 | 0.71 | CA2 (0.32) | LMNATSHRCA2CA4CA5A | |
| SCHEMBL3277117 | 0.64 | FDPS (0.47) | LMNATSHRCYTH3BTKEPN1 | |
| SCHEMBL8208273 | 0.63 | HMBS (0.92) | HMBSLMNAGAATDP1SPR | |
| SCHEMBL109490 | 0.62 | LMNA (0.71) | LMNATSHRCA2CA4CA5A | |
| SCHEMBL2171752 | 0.60 | CA2 (0.71) | LMNATSHRCA2CA4CA5A | |
| SCHEMBL4730855 | 0.60 | HMBS (0.44) | HMBSLMNATSHRCYTH3BTK | |
| SCHEMBL28993824 | 0.60 | LMNA (0.68) | LMNATSHRCA2CA4CA5A | |
| SCHEMBL31514644 | 0.60 | LMNA (0.68) | LMNATSHRCA2CA4CA5A | |
| Hydrochloric Acid SCHEMBL10917038 | 0.60 | LMNA (0.68) | LMNATSHRCA2CA4CA5A | |
| SCHEMBL4416358 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |