Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMBS | P08397 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 3/20 | 0.34 |
| ▸ | PGK2 | P07205 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784507 | 0.65 | NOTUM (0.41) | HMBSDAOLMNATSHRPGK1 | |
| Phosphoric Acid SCHEMBL15475844 | 0.63 | PGK1 (0.52) | LMNATSHRPGK1PGK2ALDH1A1 | |
| Phosphoric Acid SCHEMBL29023595 | 0.63 | PGK1 (0.52) | LMNATSHRPGK1PGK2ALDH1A1 | |
| SCHEMBL20309 | 0.63 | — | — | |
| Phosphoric Acid SCHEMBL31047197 | 0.61 | PGK1 (0.50) | LMNATSHRPGK1PGK2ALDH1A1 | |
| SCHEMBL1337277 | 0.60 | — | — | |
| SCHEMBL4727723 | 0.60 | HMBS (0.46) | HMBSLMNATSHRCYTH3BTK | |
| SCHEMBL3353801 | 0.60 | PGK1 (0.44) | LMNATSHRPGK1PGK2GAA | |
| SCHEMBL109490 | 0.60 | LMNA (0.71) | LMNATSHRGAAHPGDALDH1A1 | |
| SCHEMBL28993824 | 0.59 | LMNA (0.68) | LMNATSHRGAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |