Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727318 | 0.86 | ALDH1A1 (0.43) | CYP11B2ALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL4726892 | 0.84 | TDP2 (0.46) | CYP11B2ALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL4730197 | 0.84 | MAPK1 (0.40) | CYP11B2ALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL4728259 | 0.84 | CYP11B2 (0.40) | CYP11B2ALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL4726123 | 0.84 | TDP2 (0.41) | CYP11B2ALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL4726625 | 0.84 | CYP11B2 (0.40) | CYP11B2ALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL4784489 | 0.83 | CYP1A1 (0.41) | CYP11B2ALDH1A1MAPTL3MBTL1GLA | |
| SCHEMBL2171555 | 0.81 | ALDH1A1 (0.45) | CYP11B2ALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL4726095 | 0.80 | PPARG (0.46) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL4728618 | 0.72 | ALDH1A1 (0.48) | CYP11B2ALDH1A1MAPTL3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |