Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726625 | 0.88 | CYP11B2 (0.40) | ALDH1A1MAPTL3MBTL1CYP11B2LMNA | |
| SCHEMBL4726892 | 0.88 | TDP2 (0.46) | ALDH1A1MAPTL3MBTL1CYP11B2LMNA | |
| SCHEMBL4728259 | 0.88 | CYP11B2 (0.40) | ALDH1A1MAPTL3MBTL1CYP11B2LMNA | |
| SCHEMBL4784489 | 0.87 | CYP1A1 (0.41) | ALDH1A1MAPTL3MBTL1CYP11B2KDM4E | |
| SCHEMBL4729580 | 0.86 | CYP11B2 (0.51) | ALDH1A1MAPTL3MBTL1CYP11B2LMNA | |
| SCHEMBL4726095 | 0.82 | PPARG (0.46) | ALDH1A1L3MBTL1LMNAKMT2AMEN1 | |
| SCHEMBL4726123 | 0.81 | TDP2 (0.41) | ALDH1A1MAPTL3MBTL1CYP11B2LMNA | |
| SCHEMBL4730197 | 0.81 | MAPK1 (0.40) | ALDH1A1MAPTL3MBTL1CYP11B2LMNA | |
| SCHEMBL4727314 | 0.81 | LMNA (0.40) | ALDH1A1MAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL2171555 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1CYP11B2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |