Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.36 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728259 | 0.91 | CYP11B2 (0.40) | MAPK1ALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL4726123 | 0.86 | TDP2 (0.41) | MAPK1ALDH1A1MAPTL3MBTL1TSHR | |
| SCHEMBL4729580 | 0.84 | CYP11B2 (0.51) | ALDH1A1MAPTL3MBTL1HTTCYP11B2 | |
| SCHEMBL4730195 | 0.81 | ALPG (0.41) | MAPK1ALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL4727318 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1TSHRHTT | |
| SCHEMBL4728256 | 0.79 | ALPG (0.41) | MAPK1ALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL4726625 | 0.79 | CYP11B2 (0.40) | ALDH1A1MAPTL3MBTL1CYP11B2GAA | |
| SCHEMBL4726892 | 0.79 | TDP2 (0.46) | MAPK1ALDH1A1MAPTL3MBTL1TSHR | |
| SCHEMBL4784489 | 0.78 | CYP1A1 (0.41) | ALDH1A1MAPTL3MBTL1TSHRCYP11B2 | |
| SCHEMBL4726095 | 0.73 | PPARG (0.46) | ALDH1A1L3MBTL1SMN1; SMN2LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |