Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.42 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728914 | 0.75 | RAB9A (0.51) | SMN1; SMN2P2RX7MAPTKDM4EALDH1A1 | |
| SCHEMBL4731777 | 0.75 | RAB9A (0.51) | SMN1; SMN2P2RX7MAPTKDM4EALDH1A1 | |
| SCHEMBL12783501 | 0.74 | ALDH1A1 (0.44) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL6092524 | 0.73 | P2RX7 (0.50) | SMN1; SMN2P2RX7MAPTKDM4EALDH1A1 | |
| SCHEMBL6091141 | 0.72 | FAAH (0.49) | SMN1; SMN2P2RX7MAPTKDM4EALDH1A1 | |
| SCHEMBL4727008 | 0.72 | CNR2 (0.46) | SMN1; SMN2MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL4727194 | 0.72 | CNR2 (0.46) | SMN1; SMN2MAPTKDM4EALDH1A1NPC1 | |
| SCHEMBL27351674 | 0.72 | PTPN1 (0.46) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4729642 | 0.72 | CNR2 (0.46) | SMN1; SMN2P2RX7KDM4EALDH1A1HTT | |
| SCHEMBL6482241 | 0.72 | P2RX7 (0.58) | SMN1; SMN2P2RX7FAPALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-04-06 | — | — | US | claimed |
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074083-A1 | Cyclic and acyclic propenones for treating CNS disorders | PMP22, ADCYAP1R1, CYP11B2 | SMN1; SMN2 323/4885P2RX7 373/4885FAP 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.