Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730979 | 0.84 | TBXAS1 (0.42) | TBXAS1ALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL4734133 | 0.80 | TBXAS1 (0.40) | TBXAS1ALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL4617716 | 0.77 | TBXAS1 (0.51) | TBXAS1ALDH1A1HTTSMN1; SMN2TBXA2R | |
| SCHEMBL4619248 | 0.75 | TBXAS1 (0.53) | TBXAS1ALDH1A1HTTSMN1; SMN2TBXA2R | |
| SCHEMBL4734005 | 0.75 | TBXAS1 (0.39) | TBXAS1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL4617522 | 0.72 | TBXAS1 (0.49) | TBXAS1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL4732031 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL4737048 | 0.71 | TBXAS1 (0.39) | TBXAS1ALDH1A1HTTSMN1; SMN2PRMT5 | |
| SCHEMBL4617818 | 0.69 | SFRP1 (0.58) | TBXAS1 | |
| SCHEMBL4732619 | 0.69 | TAAR1 (0.43) | ALDH1A1HTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |