Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734165 | 0.90 | TAAR1 (0.40) | ALDH1A1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4735469 | 0.85 | ACHE (0.41) | ALDH1A1PRMT5WDR77KDM4E | |
| SCHEMBL4734005 | 0.82 | TBXAS1 (0.39) | TBXAS1ALDH1A1HTTSMN1; SMN2NAMPT | |
| SCHEMBL4734133 | 0.81 | TBXAS1 (0.40) | TBXAS1ALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL4730979 | 0.81 | TBXAS1 (0.42) | TBXAS1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4737700 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HTTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL4736394 | 0.76 | TGM2 (0.34) | — | |
| SCHEMBL4732636 | 0.76 | ACHE (0.44) | ALDH1A1HTTSMN1; SMN2PRMT5WDR77 | |
| SCHEMBL4617716 | 0.73 | TBXAS1 (0.51) | TBXAS1ALDH1A1HTTSMN1; SMN2NAMPT | |
| SCHEMBL4734290 | 0.73 | HTR1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | claimed |
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |