Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HMBS | P08397 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 3/20 | 0.31 |
| ▸ | PGK2 | P07205 | 3/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784505 | 0.74 | CA2 (0.36) | CA2CA4CA5A | |
| SCHEMBL3353801 | 0.67 | PGK1 (0.44) | CA2CA4CA5ALMNATSHR | |
| SCHEMBL20379784 | 0.67 | CA2 (0.53) | CA2CA4CA5ALMNATSHR | |
| SCHEMBL4730855 | 0.65 | HMBS (0.44) | NOTUMHMBSLMNATSHRALDH1A1 | |
| SCHEMBL27902680 | 0.63 | CA2 (0.39) | CA2CA4CA5ALMNATSHR | |
| SCHEMBL13541165 | 0.63 | CA2 (0.48) | CA2CA4CA5ALMNATSHR | |
| SCHEMBL16139781 | 0.63 | ALDH1A1 (0.43) | CA2CA4CA5ALMNATSHR | |
| SCHEMBL25825774 | 0.62 | HDAC1 (0.47) | CA2CA4CA5ALMNATSHR | |
| SCHEMBL3347914 | 0.62 | ALDH1A1 (0.46) | CA2CA4CA5ALMNATSHR | |
| SCHEMBL109490 | 0.62 | LMNA (0.71) | CA2CA4CA5ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |