Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3 | P56703 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 2/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797958 | 0.89 | DRD2 (0.38) | WNT3SFRP1BRD4BRD2BRD3 | |
| SCHEMBL4797961 | 0.87 | BRD4 (0.36) | WNT3SFRP1BRD4BRD2BRD3 | |
| SCHEMBL4733825 | 0.86 | SFRP1 (0.46) | WNT3SFRP1BRD4BRD2BRD3 | |
| SCHEMBL4735477 | 0.86 | DPP4 (0.36) | WNT3SFRP1HTR6DRD2 | |
| SCHEMBL4735151 | 0.84 | BRD4 (0.35) | WNT3SFRP1BRD4BRD2BRD3 | |
| SCHEMBL4730171 | 0.84 | SFRP1 (0.42) | WNT3SFRP1BRD4 | |
| SCHEMBL4731674 | 0.79 | PTGDR2 (0.33) | — | |
| SCHEMBL4730172 | 0.77 | SFRP1 (0.42) | WNT3SFRP1BRD4 | |
| SCHEMBL4737035 | 0.74 | BRD4 (0.43) | WNT3SFRP1BRD4BRD2BRD3 | |
| SCHEMBL4730889 | 0.72 | SFRP1 (0.48) | WNT3SFRP1BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |