Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738981 | 0.85 | LMNA (0.41) | LMNAOPRM1 | |
| SCHEMBL3821794 | 0.83 | OPRM1 (0.39) | LMNAALDH1A1TSHRMAPTNPSR1 | |
| SCHEMBL3059109 | 0.82 | ACHE (0.39) | LMNAMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL4737099 | 0.82 | ALDH1A1 (0.43) | LMNAALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL3064216 | 0.82 | ACHE (0.39) | LMNAMEN1KMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL4733711 | 0.82 | LMNA (0.39) | LMNAALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL3064159 | 0.81 | CHRM1 (0.42) | MEN1KMT2A | |
| SCHEMBL3819363 | 0.81 | ATM (0.39) | LMNAOPRM1 | |
| SCHEMBL3819801 | 0.78 | ATM (0.40) | MEN1KMT2AOPRM1 | |
| SCHEMBL3819194 | 0.78 | ATM (0.40) | ALDH1A1TSHRMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |